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8TDO
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BU of 8tdo by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient-3, variant-type morphology
Descriptor: Transthyretin
Authors:Nguyen, B.A, Singh, V, Saelices, L.
Deposit date:2023-07-04
Release date:2023-12-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nat Commun, 15, 2024
8TDN
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BU of 8tdn by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient-3, wild-type morphology
Descriptor: Transthyretin
Authors:Nguyen, B.A, Singh, V, Saelices, L.
Deposit date:2023-07-04
Release date:2023-12-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nat Commun, 15, 2024
8G9R
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BU of 8g9r by Molmil
Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
Descriptor: Transthyretin
Authors:Nguyen, B.A, Saelices, L.
Deposit date:2023-02-21
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
To Be Published
8GBR
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BU of 8gbr by Molmil
Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
Descriptor: Transthyretin
Authors:Nguyen, B.A, Saelices, L.
Deposit date:2023-02-28
Release date:2024-02-28
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
To Be Published
8E7E
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BU of 8e7e by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient
Descriptor: Transthyretin
Authors:Nguyen, B.A, Singh, V, Afrin, S, Saelices, L.
Deposit date:2022-08-23
Release date:2023-08-30
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nat Commun, 15, 2024
8E7J
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BU of 8e7j by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient
Descriptor: Transthyretin
Authors:Nguyen, B.A, Saelices, L.
Deposit date:2022-08-24
Release date:2023-08-30
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nat Commun, 15, 2024
8E7I
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BU of 8e7i by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR P24S amyloidosis patient
Descriptor: Transthyretin protein
Authors:Nguyen, B.A, Saelices, L.
Deposit date:2022-08-24
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Cardiac amyloid fibrils extracted from a variant ATTR P24S amyloidosis patient
To Be Published
8E7D
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BU of 8e7d by Molmil
Cryo-EM structure of wild-type transthyretin amyloid from heart tissue
Descriptor: Transthyretin
Authors:Nguyen, B.A, Saelices, L.
Deposit date:2022-08-23
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
To Be Published
8E7H
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BU of 8e7h by Molmil
Cryo-EM structure of cardiac amyloid fibril from a wild-type amyloidosis patient
Descriptor: Transthyretin
Authors:Nguyen, B.A, Saelices, L.
Deposit date:2022-08-23
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
To Be Published
8FNZ
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BU of 8fnz by Molmil
Acetylated tau repeat 1 and 2 fragment (AcR1R2)
Descriptor: Microtubule-associated protein tau, acetylated repeat 1 and 2 fragment
Authors:Li, L, Nguyen, A.B, Mullapudi, V, Joachimiak, L.
Deposit date:2022-12-29
Release date:2023-06-28
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.88 Å)
Cite:Disease-associated patterns of acetylation stabilize tau fibril formation.
Structure, 31, 2023
8GF7
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BU of 8gf7 by Molmil
Cryo-EM structure of serine 87 O-GlcNAc-modified alpha-synuclein fibrils
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-synuclein
Authors:Balana, J.A, Nguyen, A.B, Saelices, L, Pratt, R.M.
Deposit date:2023-03-07
Release date:2023-11-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:O-GlcNAc forces an alpha-synuclein amyloid strain with notably diminished seeding and pathology.
Nat.Chem.Biol., 20, 2024
8FQ7
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BU of 8fq7 by Molmil
Nanobody with WIW inserted in CDR3 loop to Inhibit Growth of Alzheimer's Tau fibrils
Descriptor: GLYCEROL, Nanobody with WIW insert in CDR3 loop to target tau fibrils
Authors:Abskharon, R, Sawaya, M.R, Cascio, D.C, Eisenberg, D.S.
Deposit date:2023-01-05
Release date:2023-10-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils.
Proc.Natl.Acad.Sci.USA, 120, 2023
7SP1
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BU of 7sp1 by Molmil
RNA-induced tau amyloid fibril
Descriptor: Isoform Tau-F of Microtubule-associated protein tau, RNA (5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3')
Authors:Abskharon, R, Sawaya, M.R, Boyer, D.R, Eisenberg, D.S.
Deposit date:2021-11-02
Release date:2022-03-30
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of RNA-induced tau fibrils reveals a small C-terminal core that may nucleate fibril formation.
Proc.Natl.Acad.Sci.USA, 119, 2022
7M64
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BU of 7m64 by Molmil
Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils seeded by patient extracted fibrils, polymorph 3
Descriptor: Islet amyloid polypeptide
Authors:Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2021-03-25
Release date:2021-09-22
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores
Nat.Struct.Mol.Biol., 28, 2021
7M65
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BU of 7m65 by Molmil
Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils seeded by patient extracted fibrils, polymorph 4
Descriptor: Islet amyloid polypeptide
Authors:Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2021-03-25
Release date:2021-09-22
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores
Nat.Struct.Mol.Biol., 28, 2021
7M62
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BU of 7m62 by Molmil
Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils seeded by patient extracted fibrils, polymorph 2
Descriptor: Islet amyloid polypeptide
Authors:Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2021-03-25
Release date:2021-09-22
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores
Nat.Struct.Mol.Biol., 28, 2021
7M61
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BU of 7m61 by Molmil
Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils seeded by patient extracted fibrils, polymorph 1
Descriptor: Islet amyloid polypeptide
Authors:Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2021-03-25
Release date:2021-09-22
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores
Nat.Struct.Mol.Biol., 28, 2021

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PDB entries from 2024-06-12

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