8FNZ

Acetylated tau repeat 1 and 2 fragment (AcR1R2)

Summary for 8FNZ

Entry DOI	10.2210/pdb8fnz/pdb
EMDB information	28721
Descriptor	Microtubule-associated protein tau, acetylated repeat 1 and 2 fragment (1 entity in total)
Functional Keywords	amyloid motif acetylation tau repeat domain post-translational modification, protein fibril
Biological source	Homo sapiens (human)
Total number of polymer chains	48
Total formula weight	99520.90
Authors	Li, L.,Nguyen, A.B.,Mullapudi, V.,Joachimiak, L. (deposition date: 2022-12-29, release date: 2023-06-28, Last modification date: 2023-11-15)
Primary citation	Li, L.,Nguyen, B.A.,Mullapudi, V.,Li, Y.,Saelices, L.,Joachimiak, L.A. Disease-associated patterns of acetylation stabilize tau fibril formation. Structure, 31:1025-1037.e4, 2023 Cited by PubMed: 37348495 DOI: 10.1016/j.str.2023.05.020 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.88 Å)

Structure validation