4YGV
 
 | | Reversal Agent for Dabigatran | | 分子名称: | GLYCEROL, aDabi-Fab2a heavy chain, aDabi-Fab2a light chain | | 著者 | Schiele, F, Nar, H. | | 登録日 | 2015-02-26 | | 公開日 | 2015-06-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Structure-guided residence time optimization of a dabigatran reversal agent.
Mabs, 7, 2015
|
|
4YHM
 | | Reversal Agent for Dabigatran | | 分子名称: | N-[(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazol-5-yl)carbonyl]-N-pyridin-2-yl-beta-alanine, aDabi-Fab2b heavy chain, aDabi-Fab2b light chain | | 著者 | Schiele, F, Nar, H. | | 登録日 | 2015-02-27 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Structure-guided residence time optimization of a dabigatran reversal agent.
Mabs, 7, 2015
|
|
4YHI
 | | Reversal Agent for Dabigatran | | 分子名称: | N-[(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazol-5-yl)carbonyl]-N-pyridin-2-yl-beta-alanine, aDabi-Fab2a heavy chain, aDabi-Fab2a light chain | | 著者 | Schiele, F, Nar, H. | | 登録日 | 2015-02-27 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-guided residence time optimization of a dabigatran reversal agent.
Mabs, 7, 2015
|
|
4YHN
 | | Dabigatran Reversal Agent | | 分子名称: | aDabi-Fab3 heavy chain, aDabi-Fab3 light chain | | 著者 | Schiele, F, Nar, H. | | 登録日 | 2015-02-27 | | 公開日 | 2016-02-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Structure-guided residence time optimization of a dabigatran reversal agent.
Mabs, 7, 2015
|
|
4YHO
 | | Reversal Agent for Dabigatran | | 分子名称: | N-[(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazol-5-yl)carbonyl]-N-pyridin-2-yl-beta-alanine, aDabi-Fab3 heavy chain, aDabi-Fab3 light chain | | 著者 | Schiele, F, Nar, H. | | 登録日 | 2015-02-27 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Structure-guided residence time optimization of a dabigatran reversal agent.
Mabs, 7, 2015
|
|
4YHK
 | | Reversal Agent for Dabigatran | | 分子名称: | GLYCEROL, N-[(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazol-5-yl)carbonyl]-N-pyridin-2-yl-beta-alanine, aDabi-Fab2a heavy chain, ... | | 著者 | Schiele, F, Nar, H. | | 登録日 | 2015-02-27 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structure-guided residence time optimization of a dabigatran reversal agent.
Mabs, 7, 2015
|
|
4YHL
 | | Reversal Agent for Dabigatran | | 分子名称: | aDabi-Fab2b heavy chain, aDabi-Fab2b light chain | | 著者 | Schiele, F, Nar, H. | | 登録日 | 2015-02-27 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structure-guided residence time optimization of a dabigatran reversal agent.
Mabs, 7, 2015
|
|
6Z86
 | |
6Z88
 | | human GTP cyclohydrolase I in complex with allosteric inhibitor | | 分子名称: | 5-azanyl-[1,3]thiazolo[5,4-d]pyrimidine-2,7-dione, GTP cyclohydrolase 1, ZINC ION | | 著者 | Ebenhoch, R, Nar, H. | | 登録日 | 2020-06-02 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.687 Å) | | 主引用文献 | A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6Z89
 | | human GTP cyclohydrolase I in complex with allosteric inhibitor | | 分子名称: | 5-azanyl-[1,3]thiazolo[5,4-d]pyrimidine-2,7-dione, GTP cyclohydrolase 1, ZINC ION | | 著者 | Ebenhoch, R, Nar, H. | | 登録日 | 2020-06-02 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.366 Å) | | 主引用文献 | A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6Z80
 | | stimulatory human GTP cyclohydrolase I - GFRP complex | | 分子名称: | 8-OXO-GUANOSINE-5'-TRIPHOSPHATE, GTP cyclohydrolase 1, GTP cyclohydrolase 1 feedback regulatory protein, ... | | 著者 | Ebenhoch, R, Nar, H, Vonck, J. | | 登録日 | 2020-06-02 | | 公開日 | 2020-12-09 | | 最終更新日 | 2020-12-23 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6Z87
 | | human GTP cyclohydrolase I | | 分子名称: | GTP cyclohydrolase 1, ZINC ION | | 著者 | Ebenhoch, R, Nar, H. | | 登録日 | 2020-06-02 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.564 Å) | | 主引用文献 | A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6Z85
 | | inhibitory human GTP cyclohydrolase I - GFRP complex | | 分子名称: | 7,8-DIHYDROBIOPTERIN, GTP cyclohydrolase 1, GTP cyclohydrolase 1 feedback regulatory protein, ... | | 著者 | Ebenhoch, R, Nar, H, Vonck, J. | | 登録日 | 2020-06-02 | | 公開日 | 2020-12-09 | | 最終更新日 | 2020-12-23 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
1FB1
 | | CRYSTAL STRUCTURE OF HUMAN GTP CYCLOHYDROLASE I | | 分子名称: | GTP CYCLOHYDROLASE I, ISOPROPYL ALCOHOL, ZINC ION | | 著者 | Auerbach, G, Herrmann, A, Bracher, A, Bader, G, Gutlich, M, Fischer, M, Neukamm, M, Nar, H, Garrido-Franco, M, Richardson, J, Huber, R, Bacher, A. | | 登録日 | 2000-07-14 | | 公開日 | 2000-12-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Zinc plays a key role in human and bacterial GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 97, 2000
|
|
1FBX
 | | CRYSTAL STRUCTURE OF ZINC-CONTAINING E.COLI GTP CYCLOHYDROLASE I | | 分子名称: | CHLORIDE ION, GTP CYCLOHYDROLASE I, ZINC ION | | 著者 | Auerbach, G, Herrmann, A, Bracher, A, Bader, A, Gutlich, M, Fischer, M, Neukamm, M, Nar, H, Garrido-Franco, M, Richardson, J, Huber, R, Bacher, A. | | 登録日 | 2000-07-17 | | 公開日 | 2001-02-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Zinc plays a key role in human and bacterial GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 97, 2000
|
|
1N3R
 | | Biosynthesis of pteridins. Reaction mechanism of GTP cyclohydrolase I | | 分子名称: | GTP cyclohydrolase I, GUANOSINE-5'-TRIPHOSPHATE | | 著者 | Rebelo, J, Auerbach, G, Bader, G, Bracher, A, Nar, H, Hoesl, C, Schramek, N, Kaiser, J, Bacher, A, Huber, R, Fischer, M. | | 登録日 | 2002-10-29 | | 公開日 | 2003-10-14 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Biosynthesis of Pteridines. Reaction Mechanism of GTP Cyclohydrolase I
J.MOL.BIOL., 326, 2003
|
|
1ID2
 | | CRYSTAL STRUCTURE OF AMICYANIN FROM PARACOCCUS VERSUTUS (THIOBACILLUS VERSUTUS) | | 分子名称: | AMICYANIN, COPPER (II) ION | | 著者 | Romero, A, Nar, H, Messerschmidt, A. | | 登録日 | 2001-04-03 | | 公開日 | 2001-04-11 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystal structure analysis and refinement at 2.15 A resolution of amicyanin, a type I blue copper protein, from Thiobacillus versutus.
J.Mol.Biol., 236, 1994
|
|
1N3S
 | | Biosynthesis of pteridins. Reaction mechanism of GTP cyclohydrolase I | | 分子名称: | GTP cyclohydrolase I, GUANOSINE-5'-TRIPHOSPHATE | | 著者 | Rebelo, J, Auerbach, G, Bader, G, Bracher, A, Nar, H, Hoesl, C, Schramek, N, Kaiser, J, Bacher, A, Huber, R, Fischer, M. | | 登録日 | 2002-10-29 | | 公開日 | 2004-03-02 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Biosynthesis of Pteridines. Reaction Mechanism of GTP Cyclohydrolase I
J.MOL.BIOL., 326, 2003
|
|
1N3T
 | | Biosynthesis of pteridins. Reaction mechanism of GTP cyclohydrolase I | | 分子名称: | GTP cyclohydrolase I, GUANOSINE-5'-TRIPHOSPHATE | | 著者 | Rebelo, J, Auerbach, G, Bader, G, Bracher, A, Nar, H, Hoesl, C, Schramek, N, Kaiser, J, Bacher, A, Huber, R, Fischer, M. | | 登録日 | 2002-10-29 | | 公開日 | 2003-10-14 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Biosynthesis of Pteridines. Reaction Mechanism of GTP Cyclohydrolase I
J.MOL.BIOL., 326, 2003
|
|
3E5W
 | | Crystal Structure Analysis of FP611 | | 分子名称: | Red fluorescent protein eqFP611 | | 著者 | Nienhaus, K, Nar, H, Heilker, R, Wiedenmann, J, Nienhaus, G.U. | | 登録日 | 2008-08-14 | | 公開日 | 2008-09-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Trans-cis isomerization is responsible for the red-shifted fluorescence in variants of the red fluorescent protein eqFP611.
J.Am.Chem.Soc., 130, 2008
|
|
6SVK
 | | human Myeloid-derived growth factor (MYDGF) | | 分子名称: | MALONATE ION, Myeloid-derived growth factor | | 著者 | Ebenhoch, R, Nar, H. | | 登録日 | 2019-09-18 | | 公開日 | 2019-11-27 | | 最終更新日 | 2019-12-04 | | 実験手法 | X-RAY DIFFRACTION (1.604 Å) | | 主引用文献 | Crystal structure and receptor-interacting residues of MYDGF - a protein mediating ischemic tissue repair.
Nat Commun, 10, 2019
|
|
2UV5
 | | Crystal Structure of a CBS domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP | | 分子名称: | 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE | | 著者 | Day, P, Sharff, A, Parra, L, Cleasby, A, Williams, M, Horer, S, Nar, H, Redemann, N, Tickle, I, Yon, J. | | 登録日 | 2007-03-09 | | 公開日 | 2007-05-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Structure of a Cbs-Domain Pair from the Regulatory Gamma1 Subunit of Human Ampk in Complex with AMP and Zmp.
Acta Crystallogr.,Sect.D, 63, 2007
|
|
2UV7
 | | Crystal Structure of a CBS domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP | | 分子名称: | 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ADENOSINE MONOPHOSPHATE | | 著者 | Day, P, Sharff, A, Parra, L, Cleasby, A, Williams, M, Horer, S, Nar, H, Redemann, N, Tickle, I, Yon, J. | | 登録日 | 2007-03-09 | | 公開日 | 2007-05-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of a Cbs-Domain Pair from the Regulatory Gamma1 Subunit of Human Ampk in Complex with AMP and Zmp.
Acta Crystallogr.,Sect.D, 63, 2007
|
|
2UV6
 | | Crystal Structure of a CBS domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP | | 分子名称: | 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ADENOSINE MONOPHOSPHATE | | 著者 | Day, P, Sharff, A, Parra, L, Cleasby, A, Williams, M, Horer, S, Nar, H, Redemann, N, Tickle, I, Yon, J. | | 登録日 | 2007-03-09 | | 公開日 | 2007-05-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of a Cbs-Domain Pair from the Regulatory Gamma1 Subunit of Human Ampk in Complex with AMP and Zmp.
Acta Crystallogr.,Sect.D, 63, 2007
|
|
2UV4
 | | Crystal Structure of a CBS domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP | | 分子名称: | 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ADENOSINE MONOPHOSPHATE | | 著者 | Day, P, Sharff, A, PArra, L, Cleasby, A, Williams, M, Horer, S, Nar, H, Redemann, N, Tickle, I, Yon, J. | | 登録日 | 2007-03-09 | | 公開日 | 2007-05-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | | 主引用文献 | Structure of a Cbs-Domain Pair from the Regulatory Gamma1 Subunit of Human Ampk in Complex with AMP and Zmp.
Acta Crystallogr.,Sect.D, 63, 2007
|
|
