1FB1

CRYSTAL STRUCTURE OF HUMAN GTP CYCLOHYDROLASE I

Summary for 1FB1

• Entry DOI: 10.2210/pdb1fb1/pdb
• Descriptor: GTP CYCLOHYDROLASE I, ZINC ION, ISOPROPYL ALCOHOL (3 entities in total)
• Functional Keywords: hydrolase, allosteric enzyme, phosphorylation
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P30793
• Total number of polymer chains: 5
• Total formula weight: 111154.96

Authors

Auerbach, G.,Herrmann, A.,Bracher, A.,Bader, G.,Gutlich, M.,Fischer, M.,Neukamm, M.,Nar, H.,Garrido-Franco, M.,Richardson, J.,Huber, R.,Bacher, A. (deposition date: 2000-07-14, release date: 2000-12-08, Last modification date: 2024-02-07)

• Primary citation: Auerbach, G.,Herrmann, A.,Bracher, A.,Bader, G.,Gutlich, M.,Fischer, M.,Neukamm, M.,Garrido-Franco, M.,Richardson, J.,Nar, H.,Huber, R.,Bacher, A.; Zinc plays a key role in human and bacterial GTP cyclohydrolase I.; Proc.Natl.Acad.Sci.USA, 97:13567-13572, 2000; PubMed: 11087827; DOI: 10.1073/pnas.240463497

Experimental method

X-RAY DIFFRACTION (3.1 Å)