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3GJX
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BU of 3gjx by Molmil
Crystal Structure of the Nuclear Export Complex CRM1-Snurportin1-RanGTP
Descriptor: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ...
Authors:Monecke, T, Guettler, T, Neumann, P, Dickmanns, A, Goerlich, D, Ficner, R.
Deposit date:2009-03-09
Release date:2009-05-26
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Nuclear Export Receptor CRM1 in Complex with Snurportin1 and RanGTP.
Science, 2009
4FGV
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BU of 4fgv by Molmil
Crystal structure of free CRM1 (crystal form 1)
Descriptor: Chromosome region maintenance 1 (CRM1) or Exportin 1 (Xpo1)
Authors:Monecke, T, Neumann, P, Dickmanns, A, Ficner, R.
Deposit date:2012-06-05
Release date:2013-01-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.941 Å)
Cite:Structural basis for cooperativity of CRM1 export complex formation.
Proc.Natl.Acad.Sci.USA, 110, 2013
3GDH
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BU of 3gdh by Molmil
Methyltransferase domain of human Trimethylguanosine Synthase 1 (TGS1) bound to m7GTP and adenosyl-homocysteine (active form)
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, R-1,2-PROPANEDIOL, S-1,2-PROPANEDIOL, ...
Authors:Monecke, T, Dickmanns, A, Ficner, R.
Deposit date:2009-02-24
Release date:2009-06-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for m7G-cap hypermethylation of small nuclear, small nucleolar and telomerase RNA by the dimethyltransferase TGS1.
Nucleic Acids Res., 37, 2009
4HZK
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BU of 4hzk by Molmil
Crystal structure of free CRM1 (crystal form 2)
Descriptor: CRM1 Nuclear transport receptor
Authors:Monecke, T, Neumann, P, Dickmanns, A, Ficner, R.
Deposit date:2012-11-15
Release date:2013-01-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for cooperativity of CRM1 export complex formation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4NV0
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BU of 4nv0 by Molmil
Crystal structure of cytosolic 5'-nucleotidase IIIB (cN-IIIB) bound to 7-methylguanosine
Descriptor: 7-METHYLGUANOSINE, 7-methylguanosine phosphate-specific 5'-nucleotidase, MAGNESIUM ION, ...
Authors:Monecke, T, Neumann, P, Ficner, R.
Deposit date:2013-12-04
Release date:2014-03-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal Structures of the Novel Cytosolic 5'-Nucleotidase IIIB Explain Its Preference for m7GMP
Plos One, 9, 2014
4NWI
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BU of 4nwi by Molmil
Crystal structure of cytosolic 5'-nucleotidase IIIB (cN-IIIB) bound to cytidine
Descriptor: 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, 7-methylguanosine phosphate-specific 5'-nucleotidase, CHLORIDE ION, ...
Authors:Monecke, T, Neumann, P, Ficner, R.
Deposit date:2013-12-06
Release date:2014-03-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structures of the Novel Cytosolic 5'-Nucleotidase IIIB Explain Its Preference for m7GMP
Plos One, 9, 2014
3CTR
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BU of 3ctr by Molmil
Crystal structure of the RRM-domain of the poly(A)-specific ribonuclease PARN bound to m7GTP
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Poly(A)-specific ribonuclease PARN
Authors:Monecke, T, Schell, S, Dickmanns, A, Ficner, R.
Deposit date:2008-04-14
Release date:2008-07-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the RRM domain of poly(A)-specific ribonuclease reveals a novel m(7)G-cap-binding mode.
J.Mol.Biol., 382, 2008
3EGI
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BU of 3egi by Molmil
Methyltransferase domain of human trimethylguanosine synthase TGS1 bound to m7GpppA (inactive form)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Trimethylguanosine synthase homolog
Authors:Monecke, T, Dickmanns, A, Ficner, R.
Deposit date:2008-09-10
Release date:2009-03-31
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structure analysis of the conserved methyltransferase domain of human trimethylguanosine synthase TGS1.
Acta Crystallogr.,Sect.D, 65, 2009
5DIS
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BU of 5dis by Molmil
Crystal structure of a CRM1-RanGTP-SPN1 export complex bound to a 113 amino acid FG-repeat containing fragment of Nup214
Descriptor: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Monecke, T, Port, S.A, Dickmanns, A, Kehlenbach, R.H, Ficner, R.
Deposit date:2015-09-01
Release date:2015-11-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural and Functional Characterization of CRM1-Nup214 Interactions Reveals Multiple FG-Binding Sites Involved in Nuclear Export.
Cell Rep, 13, 2015
3NC0
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BU of 3nc0 by Molmil
Crystal structure of the HIV-1 Rev NES-CRM1-RanGTP nuclear export complex (crystal II)
Descriptor: DI(HYDROXYETHYL)ETHER, Exportin-1, GLYCEROL, ...
Authors:Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
3NBY
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BU of 3nby by Molmil
Crystal structure of the PKI NES-CRM1-RanGTP nuclear export complex
Descriptor: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
3NBZ
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BU of 3nbz by Molmil
Crystal structure of the HIV-1 Rev NES-CRM1-RanGTP nuclear export complex (crystal I)
Descriptor: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
3NC1
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BU of 3nc1 by Molmil
Crystal structure of the CRM1-RanGTP complex
Descriptor: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
4NOX
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BU of 4nox by Molmil
Structure of the nine-bladed beta-propeller of eIF3b
Descriptor: CHLORIDE ION, Eukaryotic translation initiation factor 3 subunit B
Authors:Liu, Y, Neumann, P, Kuhle, B, Monecke, T, Ficner, R.
Deposit date:2013-11-20
Release date:2014-09-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.722 Å)
Cite:Translation initiation factor eIF3b contains a nine-bladed beta-propeller and interacts with the 40S ribosomal subunit
Structure, 22, 2014
2L1L
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BU of 2l1l by Molmil
NMR Solution Structure of the Phi0 PKI NES Peptide in Complex with CRM1-RanGTP
Descriptor: Exportin-1, cAMP-dependent protein kinase inhibitor alpha
Authors:Madl, T, Sattler, M.
Deposit date:2010-07-29
Release date:2011-06-15
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
6YMC
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BU of 6ymc by Molmil
26-mer stem-loop RNA
Descriptor: BARIUM ION, RNA (26-MER)
Authors:Janowski, R, Niessing, D.
Deposit date:2020-04-08
Release date:2022-04-20
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:Multiple intrinsically disordered RNA-binding motifs cooperate as RNA-folding catalyst and mediate phase transition
To Be Published
8CHW
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BU of 8chw by Molmil
Crystal structure of human PURA (fragment Pro216-Lys280, PUR repeat III)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Transcriptional activator protein Pur-alpha
Authors:Janowski, R, Niessing, D.
Deposit date:2023-02-08
Release date:2024-02-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:PURA syndrome-causing mutations impair PUR-domain integrity and affect P-body association.
Elife, 13, 2024
8CHT
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BU of 8cht by Molmil
Crystal structure of human PURA (fragment Glu57-Glu212, PUR repeat I and II)
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Transcriptional activator protein Pur-alpha
Authors:Janowski, R, Niessing, D.
Deposit date:2023-02-08
Release date:2024-02-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:PURA syndrome-causing mutations impair PUR-domain integrity and affect P-body association.
Elife, 13, 2024
8CHV
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BU of 8chv by Molmil
Crystal structure of human PURA (fragment Glu57-Glu212, PUR repeat I and II) R140P mutant
Descriptor: Transcriptional activator protein Pur-alpha
Authors:Janowski, R, Niessing, D.
Deposit date:2023-02-08
Release date:2024-02-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:PURA syndrome-causing mutations impair PUR-domain integrity and affect P-body association.
Elife, 13, 2024
8CHU
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BU of 8chu by Molmil
Crystal structure of human PURA repeat I-II K97E mutant
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, Transcriptional activator protein Pur-alpha
Authors:Janowski, R, Niessing, D.
Deposit date:2023-02-08
Release date:2024-02-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:PURA syndrome-causing mutations impair PUR-domain integrity and affect P-body association.
Elife, 13, 2024

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