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3EGI

Methyltransferase domain of human trimethylguanosine synthase TGS1 bound to m7GpppA (inactive form)

Summary for 3EGI
Entry DOI10.2210/pdb3egi/pdb
DescriptorTrimethylguanosine synthase homolog, ADENOSINE-5'-DIPHOSPHATE (3 entities in total)
Functional Keywordsmethyltransferase-domain, alpha-beta-alpha sandwich, methyltransferase, nucleus, transcription, transcription regulation, transferase
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm: Q96RS0
Total number of polymer chains4
Total formula weight92891.01
Authors
Monecke, T.,Dickmanns, A.,Ficner, R. (deposition date: 2008-09-10, release date: 2009-03-31, Last modification date: 2012-04-18)
Primary citationMonecke, T.,Dickmanns, A.,Strasser, A.,Ficner, R.
Structure analysis of the conserved methyltransferase domain of human trimethylguanosine synthase TGS1.
Acta Crystallogr.,Sect.D, 65:332-338, 2009
Cited by
PubMed: 19307714
DOI: 10.1107/S0907444909003102
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.21 Å)
Structure validation

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