3EGI
Methyltransferase domain of human trimethylguanosine synthase TGS1 bound to m7GpppA (inactive form)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Trimethylguanosine synthase homolog | polymer | 206 | 22795.6 | 4 | UniProt (Q96RS0) Pfam (PF09445) | Homo sapiens (Human) | Nuclear receptor coactivator 6-interacting protein, PRIP-interacting protein with methyltransferase motif, PIPMT, PIMT, CLL-associated antigen KW-2, Hepatocellular carcinoma-associated antigen 137 |
| 2 | E, F, G, H (A, B, C, D) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 631 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 653 - 853 (UniProt: Q96RS0)
| PDB | External Database | Details |
|---|---|---|
| Gly 648 | - | expression tag |
| Pro 649 | - | expression tag |
| Leu 650 | - | expression tag |
| Gly 651 | - | expression tag |
| Ser 652 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 91182.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1708.8 | |
| All* | Total formula weight | 92891.0 |
