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8CHU

Crystal structure of human PURA repeat I-II K97E mutant

Summary for 8CHU
Entry DOI10.2210/pdb8chu/pdb
DescriptorTranscriptional activator protein Pur-alpha, 1,2-ETHANEDIOL, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordsrna/dna binding, pur repeat, pc4-like fold, rna binding protein
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight35880.75
Authors
Janowski, R.,Niessing, D. (deposition date: 2023-02-08, release date: 2024-02-21)
Primary citationJanowski, R.,Niessing, D.
PURA Syndrome-causing mutations impair PUR-domain integrity and affect P-body association
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.45 Å)
Structure validation

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PDB entries from 2024-04-24

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