8CHU
Crystal structure of human PURA repeat I-II K97E mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transcriptional activator protein Pur-alpha | polymer | 158 | 17897.2 | 2 | UniProt (Q00577) Pfam (PF04845) | Homo sapiens (human) | Purine-rich single-stranded DNA-binding protein alpha |
| 2 | C (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 3 | D (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 87 | Chemie (HOH) |
Sequence modifications
A, B: 57 - 212 (UniProt: Q00577)
| PDB | External Database | Details |
|---|---|---|
| Gly 55 | - | expression tag |
| Pro 56 | - | expression tag |
| Glu 97 | Lys 97 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35794.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 86.4 | |
| All* | Total formula weight | 35880.8 |
