8CHV

Crystal structure of human PURA (fragment Glu57-Glu212, PUR repeat I and II) R140P mutant

Summary for 8CHV

• Entry DOI: 10.2210/pdb8chv/pdb
• Descriptor: Transcriptional activator protein Pur-alpha (2 entities in total)
• Functional Keywords: rna/dna binding, pur repeat, pc4-like fold, rna binding protein, pura syndrome
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 70732.05

Authors

Janowski, R.,Niessing, D. (deposition date: 2023-02-08, release date: 2024-02-21)

• Primary citation: Janowski, R.,Niessing, D.; PURA Syndrome-causing mutations impair PUR-domain integrity and affect P-body association; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.15 Å)