2L1L

NMR Solution Structure of the Phi0 PKI NES Peptide in Complex with CRM1-RanGTP

Summary for 2L1L

• Entry DOI: 10.2210/pdb2l1l/pdb
• Descriptor: cAMP-dependent protein kinase inhibitor alpha, Exportin-1 (2 entities in total)
• Functional Keywords: nuclear export, pki nes, crm1, rangtp, nuclear protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: O14980
• Total number of polymer chains: 2
• Total formula weight: 17562.32

Authors

Madl, T.,Sattler, M. (deposition date: 2010-07-29, release date: 2011-06-15, Last modification date: 2011-07-13)

• Primary citation: Guttler, T.,Madl, T.,Neumann, P.,Deichsel, D.,Corsini, L.,Monecke, T.,Ficner, R.,Sattler, M.,Gorlich, D.; NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.; Nat.Struct.Mol.Biol., 17:1367-1376, 2010; PubMed: 20972448; DOI: 10.1038/nsmb.1931

Experimental method

SOLUTION NMR