3NG5
 
 | | Crystal Structure of V30M transthyretin complexed with (-)-epigallocatechin gallate (EGCG) | | Descriptor: | (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate, GLYCEROL, Transthyretin | | Authors: | Miyata, M, Nakamura, T, Ikemizu, S, Chirifu, M, Yamagata, Y, Kai, H. | | Deposit date: | 2010-06-11 | | Release date: | 2010-07-07 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of green tea polyphenol(-)-epigallocatechin gallate (EGCG)-transthyretin complex reveals novel binding site distinct from thyroxine binding site
Biochemistry, 2010
|
|
6LCE
 | |
6LCF
 | | Crystal Structure of beta-L-arabinobiose binding protein - native | | Descriptor: | ABC transporter substrate binding component, beta-L-arabinofuranose-(1-2)-beta-L-arabinofuranose | | Authors: | Miyake, M, Arakawa, T, Fushinobu, S. | | Deposit date: | 2019-11-18 | | Release date: | 2020-04-22 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Structural analysis of beta-L-arabinobiose-binding protein in the metabolic pathway of hydroxyproline-rich glycoproteins in Bifidobacterium longum.
Febs J., 287, 2020
|
|
209D
 | | Structural, physical and biological characteristics of RNA:DNA binding agent N8-actinomycin D | | Descriptor: | DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3'), N8-ACTINOMYCIN D | | Authors: | Shinomiya, M, Chu, W, Carlson, R.G, Weaver, R.F, Takusagawa, F. | | Deposit date: | 1995-05-01 | | Release date: | 1995-10-15 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural, Physical, and Biological Characteristics of RNA.DNA Binding Agent N8-Actinomycin D.
Biochemistry, 34, 1995
|
|
3A4D
 | | Crystal structure of Human Transthyretin (wild-type) | | Descriptor: | GLYCEROL, SULFATE ION, Transthyretin | | Authors: | Miyata, M. | | Deposit date: | 2009-07-06 | | Release date: | 2009-12-22 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Role of the Glutamic Acid 54 Residue in Transthyretin Stability and Thyroxine Binding
Biochemistry, 2009
|
|
3A4F
 | | Crystal Structure of Human Transthyretin (E54K) | | Descriptor: | GLYCEROL, SULFATE ION, Transthyretin | | Authors: | Miyata, M, Sato, T, Nakamura, T, Ikemizu, S, Yamagata, Y, Kai, H. | | Deposit date: | 2009-07-06 | | Release date: | 2009-12-22 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Role of the glutamic acid 54 residue in transthyretin stability and thyroxine binding
Biochemistry, 49, 2010
|
|
3A4E
 | | Crystal structure of Human Transthyretin (E54G) | | Descriptor: | GLYCEROL, SULFATE ION, Transthyretin | | Authors: | Miyata, M, Sato, T, Nakamura, T, Ikemizu, S, Yamagata, Y, Kai, H. | | Deposit date: | 2009-07-06 | | Release date: | 2009-12-22 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Role of the glutamic acid 54 residue in transthyretin stability and thyroxine binding
Biochemistry, 49, 2010
|
|
2RPS
 | | Solution structure of a novel insect chemokine isolated from integument | | Descriptor: | Chemokine | | Authors: | Kamiya, M, Nakatogawa, S, Oda, Y, Kamijima, T, Aizawa, T, Demura, M, Hayakawa, Y, Kawano, K. | | Deposit date: | 2008-07-28 | | Release date: | 2009-06-16 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | A novel peptide mediates aggregation and migration of hemocytes from an insect
Curr.Biol., 19, 2009
|
|
2YW9
 | |
1PD2
 | |
3VZV
 | | Crystal structure of human mdm2 with a dihydroimidazothiazole inhibitor | | Descriptor: | 1-{[(5R,6S)-5,6-bis(4-chlorophenyl)-6-methyl-3-(propan-2-yl)-5,6-dihydroimidazo[2,1-b][1,3]thiazol-2-yl]carbonyl}-N,N-dimethyl-L-prolinamide, E3 ubiquitin-protein ligase Mdm2 | | Authors: | Shimizu, H, Katakura, S, Miyazaki, M, Naito, H, Sugimoto, Y, Kawato, H, Okayama, T, Soga, T. | | Deposit date: | 2012-10-16 | | Release date: | 2013-02-06 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Lead optimization of novel p53-MDM2 interaction inhibitors possessing dihydroimidazothiazole scaffold
Bioorg.Med.Chem.Lett., 23, 2013
|
|
3W69
 | | Crystal structure of human mdm2 with a dihydroimidazothiazole inhibitor | | Descriptor: | (5R,6S)-2-[((2S,5R)-2-{[(3R)-4-acetyl-3-methylpiperazin-1-yl]carbonyl}-5-ethylpyrrolidin-1-yl)carbonyl]-5,6-bis(4-chlorophenyl)-3-isopropyl-6-methyl-5,6-dihydroimidazo[2,1-b][1,3]thiazole, E3 ubiquitin-protein ligase Mdm2, SULFATE ION | | Authors: | Shimizu, H, Katakura, S, Miyazaki, M, Naito, H, Sugimoto, Y, Kawato, H, Okayama, T, Soga, T. | | Deposit date: | 2013-02-12 | | Release date: | 2013-06-05 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Synthesis and evaluation of novel orally active p53-MDM2 interaction inhibitors
Bioorg.Med.Chem., 21, 2013
|
|
2ZIY
 | | Crystal structure of squid rhodopsin | | Descriptor: | PALMITIC ACID, RETINAL, Rhodopsin | | Authors: | Miyano, M, Shimamura, T. | | Deposit date: | 2008-02-27 | | Release date: | 2008-05-06 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Crystal structure of squid rhodopsin with intracellularly extended cytoplasmic region
J.Biol.Chem., 283, 2008
|
|
2D55
 | | Structural, physical and biological characteristics of RNA.DNA binding agent N8-actinomycin D | | Descriptor: | ACTINOMYCIN D, DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3') | | Authors: | Shinomiya, M, Chu, W, Carlson, R.G, Weaver, R.F, Takusagawa, F. | | Deposit date: | 1995-05-01 | | Release date: | 1995-10-15 | | Last modified: | 2024-07-10 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal Structure of the 2:1 Complex between D(Gaagcttc) and the Anticancer Drug Actinomycin D.
J.Mol.Biol., 225, 1992
|
|
2RN2
 | | STRUCTURAL DETAILS OF RIBONUCLEASE H FROM ESCHERICHIA COLI AS REFINED TO AN ATOMIC RESOLUTION | | Descriptor: | RIBONUCLEASE H | | Authors: | Katayanagi, K, Miyagawa, M, Matsushima, M, Ishikawa, M, Kanaya, S, Nakamura, H, Ikehara, M, Matsuzaki, T, Morikawa, K. | | Deposit date: | 1992-04-15 | | Release date: | 1993-10-31 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | Structural details of ribonuclease H from Escherichia coli as refined to an atomic resolution.
J.Mol.Biol., 223, 1992
|
|
3MHZ
 | | 1.7A structure of 2-fluorohistidine labeled Protective Antigen | | Descriptor: | CALCIUM ION, Protective antigen, TETRAETHYLENE GLYCOL | | Authors: | Lovell, S, Battaile, K.P, Wimalasena, D.S, Janowiak, B.E, Miyagi, M, Sun, J, Hajduch, J, Pooput, C, Kirk, K.L, Bann, J.G. | | Deposit date: | 2010-04-09 | | Release date: | 2010-08-11 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Evidence that histidine protonation of receptor-bound anthrax protective antigen is a trigger for pore formation.
Biochemistry, 49, 2010
|
|
1IRS
 | | IRS-1 PTB DOMAIN COMPLEXED WITH A IL-4 RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE | | Descriptor: | IL-4 RECEPTOR PHOSPHOPEPTIDE, IRS-1 | | Authors: | Zhou, M.-M, Huang, B, Olejniczak, E.T, Meadows, R.P, Shuker, S.B, Miyazaki, M, Trub, T, Shoelson, S.E, Feisk, S.W. | | Deposit date: | 1996-03-22 | | Release date: | 1997-05-15 | | Last modified: | 2024-10-09 | | Method: | SOLUTION NMR | | Cite: | Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain.
Nat.Struct.Biol., 3, 1996
|
|
1J1Y
 | | Crystal Structure of PaaI from Thermus thermophilus HB8 | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, PaaI protein | | Authors: | Kunishima, N, Sugahara, M, Kuramitsu, S, Yokoyama, S, Miyano, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2002-12-24 | | Release date: | 2004-02-17 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | A Novel Induced-fit Reaction Mechanism of Asymmetric Hot Dog Thioesterase PaaI
J.Mol.Biol., 352, 2005
|
|
3PCV
 | | Crystal structure analysis of human leukotriene C4 synthase at 1.9 angstrom resolution | | Descriptor: | 1,2-ETHANEDIOL, DODECYL-BETA-D-MALTOSIDE, GLUTATHIONE, ... | | Authors: | Saino, H, Ago, H, Miyano, M. | | Deposit date: | 2010-10-22 | | Release date: | 2011-03-16 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The catalytic architecture of leukotriene C4 synthase with two arginine residues
J.Biol.Chem., 286, 2011
|
|
1J2W
 | | Tetrameric Structure of aldolase from Thermus thermophilus HB8 | | Descriptor: | Aldolase protein | | Authors: | Lokanath, N.K, Shiromizu, I, Miyano, M, Yokoyama, S, Kuramitsu, S, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-01-14 | | Release date: | 2003-04-08 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure of aldolase from Thermus thermophilus HB8 showing the contribution of oligomeric state to thermostability.
Acta Crystallogr.,Sect.D, 60, 2004
|
|
1APA
 | | X-RAY STRUCTURE OF A POKEWEED ANTIVIRAL PROTEIN, CODED BY A NEW GENOMIC CLONE, AT 0.23 NM RESOLUTION. A MODEL STRUCTURE PROVIDES A SUITABLE ELECTROSTATIC FIELD FOR SUBSTRATE BINDING. | | Descriptor: | POKEWEED ANTIVIRAL PROTEIN | | Authors: | Ago, H, Kataoka, J, Tsuge, H, Habuka, N, Inagaki, E, Noma, M, Miyano, M. | | Deposit date: | 1993-09-21 | | Release date: | 1994-01-31 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | X-ray structure of a pokeweed antiviral protein, coded by a new genomic clone, at 0.23 nm resolution. A model structure provides a suitable electrostatic field for substrate binding.
Eur.J.Biochem., 225, 1994
|
|
2MDB
 | | Tachyplesin I in the presence of lipopolysaccharide | | Descriptor: | Tachyplesin-1 | | Authors: | Kushibiki, T, Kamiya, M, Aizawa, T, Kumaki, Y, Kikukawa, T, Mizuguchi, M, Demura, M, Kawabata, S.I, Kawano, K. | | Deposit date: | 2013-09-09 | | Release date: | 2014-02-19 | | Last modified: | 2024-10-16 | | Method: | SOLUTION NMR | | Cite: | Interaction between tachyplesin I, an antimicrobial peptide derived from horseshoe crab, and lipopolysaccharide.
Biochim.Biophys.Acta, 1844, 2014
|
|
2N92
 | | Solution structure of cecropin P1 with LPS | | Descriptor: | Cecropin-P1 | | Authors: | Baek, M, Kamiya, M, Kushibiki, T, Nakazumi, T, Tomisawa, S, Abe, C, Kumaki, Y, Kikukawa, T, Demura, M, Kawano, K, Aizawa, T. | | Deposit date: | 2015-11-04 | | Release date: | 2016-11-09 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Lipopolysaccharide bound structure of antimicrobial peptide cecropin P1 by NMR spectroscopy
To be Published
|
|
2RTV
 | | Tachyplesin I in water | | Descriptor: | Tachyplesin-1 | | Authors: | Kushibiki, T, Kamiya, M, Aizawa, T, Kumaki, Y, Kikukawa, T, Mizuguchi, M, Demura, M, Kawabata, S.I, Kawano, K. | | Deposit date: | 2013-09-19 | | Release date: | 2014-02-19 | | Last modified: | 2024-10-16 | | Method: | SOLUTION NMR | | Cite: | Interaction between tachyplesin I, an antimicrobial peptide derived from horseshoe crab, and lipopolysaccharide.
Biochim.Biophys.Acta, 1844, 2014
|
|
1DP4
 | | DIMERIZED HORMONE BINDING DOMAIN OF THE ATRIAL NATRIURETIC PEPTIDE RECEPTOR | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATRIAL NATRIURETIC PEPTIDE RECEPTOR A, ... | | Authors: | van den Akker, F, Zhang, X, Miyagi, M, Huo, X, Misono, K.S, Yee, V.C. | | Deposit date: | 1999-12-23 | | Release date: | 2000-07-12 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of the dimerized hormone-binding domain of a guanylyl-cyclase-coupled receptor.
Nature, 406, 2000
|
|
