3MHZ

1.7A structure of 2-fluorohistidine labeled Protective Antigen

Summary for 3MHZ

Entry DOI	10.2210/pdb3mhz/pdb
Descriptor	Protective antigen, CALCIUM ION, TETRAETHYLENE GLYCOL, ... (4 entities in total)
Functional Keywords	anthrax, toxin, 2-fluorohistidine, pore, histidine, receptor, hydrogen bonding
Biological source	Bacillus anthracis (anthrax,anthrax bacterium)
Cellular location	Secreted, extracellular space: P13423
Total number of polymer chains	1
Total formula weight	83223.12
Authors	Lovell, S.,Battaile, K.P.,Wimalasena, D.S.,Janowiak, B.E.,Miyagi, M.,Sun, J.,Hajduch, J.,Pooput, C.,Kirk, K.L.,Bann, J.G. (deposition date: 2010-04-09, release date: 2010-08-11, Last modification date: 2023-09-06)
Primary citation	Wimalasena, D.S.,Janowiak, B.E.,Lovell, S.,Miyagi, M.,Sun, J.,Zhou, H.,Hajduch, J.,Pooput, C.,Kirk, K.L.,Battaile, K.P.,Bann, J.G. Evidence that histidine protonation of receptor-bound anthrax protective antigen is a trigger for pore formation. Biochemistry, 49:6973-6983, 2010 Cited by PubMed: 20672855 DOI: 10.1021/bi100647z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation