3A4E
Crystal structure of Human Transthyretin (E54G)
Summary for 3A4E
Entry DOI | 10.2210/pdb3a4e/pdb |
Related | 3A4D 3A4F |
Descriptor | Transthyretin, GLYCEROL, SULFATE ION, ... (4 entities in total) |
Functional Keywords | beta barrel, amyloid, amyloidosis, disease mutation, gamma-carboxyglutamic acid, glycoprotein, hormone, neuropathy, retinol-binding, secreted, thyroid hormone, transport, vitamin a, transport protein, thyroxine |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 2 |
Total formula weight | 27879.01 |
Authors | Miyata, M.,Sato, T.,Nakamura, T.,Ikemizu, S.,Yamagata, Y.,Kai, H. (deposition date: 2009-07-06, release date: 2009-12-22, Last modification date: 2023-11-01) |
Primary citation | Miyata, M.,Sato, T.,Mizuguchi, M.,Nakamura, T.,Ikemizu, S.,Nabeshima, Y.,Susuki, S.,Suwa, Y.,Morioka, H.,Ando, Y.,Suico, M.A.,Shuto, T.,Koga, T.,Yamagata, Y.,Kai, H. Role of the glutamic acid 54 residue in transthyretin stability and thyroxine binding Biochemistry, 49:114-123, 2010 Cited by PubMed: 19950966DOI: 10.1021/bi901677z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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