5W7Y
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5W7W
| Crystal Structure of FHA domain of human APLF | Descriptor: | Aprataxin and PNK-like factor, FORMIC ACID, SODIUM ION | Authors: | Pedersen, L.C, Kim, K, London, R.E. | Deposit date: | 2017-06-21 | Release date: | 2018-05-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.348 Å) | Cite: | Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications. Nucleic Acids Res., 45, 2017
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3MQ1
| Crystal Structure of Dust Mite Allergen Der p 5 | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Mite allergen Der p 5, ... | Authors: | Mueller, G.A, Gosavi, R.A, Krahn, J.M, Edwards, L.L, Cuneo, M.J, Glesner, J, Pomes, A, Chapman, M.D, London, R.E, Pedersen, L.C. | Deposit date: | 2010-04-27 | Release date: | 2010-06-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Der p 5 crystal structure provides insight into the group 5 dust mite allergens. J.Biol.Chem., 285, 2010
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5E6Q
| Importin alpha binding to XRCC1 NLS peptide | Descriptor: | CHLORIDE ION, DNA repair protein XRCC1 NLS peptide, GLYCEROL, ... | Authors: | Pedersen, L.C, Kirby, T.W, Gassman, N.R, Smith, C.E, Gabel, S.A, Sobhany, M, Wilson, S.H, London, R.E. | Deposit date: | 2015-10-10 | Release date: | 2015-10-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.305 Å) | Cite: | Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS. Sci Rep, 5, 2015
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6VCJ
| Crystal structure of hsDHFR in complex with NADP+, DAP, and R-naproxen | Descriptor: | (2R)-2-(6-methoxynaphthalen-2-yl)propanoic acid, Dihydrofolate reductase, FOLIC ACID, ... | Authors: | Pedersen, L.C, London, R.E, Gabel, S.A, Krahn, J.M, DeRose, E.F. | Deposit date: | 2019-12-21 | Release date: | 2020-10-28 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | The Structural Basis for Nonsteroidal Anti-Inflammatory Drug Inhibition of Human Dihydrofolate Reductase. J.Med.Chem., 63, 2020
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3H4Z
| Crystal Structure of an MBP-Der p 7 fusion protein | Descriptor: | Maltose-binding periplasmic protein fused with Allergen DERP7, SODIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Pedersen, L.C, Mueller, G.A, London, R.E. | Deposit date: | 2009-04-21 | Release date: | 2010-03-31 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The structure of the dust mite allergen Der p 7 reveals similarities to innate immune proteins. J.Allergy Clin.Immunol., 125, 2010
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5W7X
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4JRB
| Structure of Cockroach Allergen Bla g 1 Tandem Repeat as a EGFP fusion | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, CHLORIDE ION, DODECANE, ... | Authors: | Mueller, G.A, Pedersen, L.C, Lih, F.B, Glesner, J, Moon, A.F, Chapman, M.D, Tomer, K, London, R.E. | Deposit date: | 2013-03-21 | Release date: | 2013-07-24 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.414 Å) | Cite: | The novel structure of the cockroach allergen Bla g 1 has implications for allergenicity and exposure assessment. J.Allergy Clin.Immunol., 132, 2013
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4KSE
| Crystal structure of a HIV p51 (219-230) deletion mutant | Descriptor: | 1,2-ETHANEDIOL, HIV p51 subunit | Authors: | Zheng, X, Mueller, G.A, Derose, E.F, Pedersen, L.C, Gabel, S.A, Cuneo, M.J, Krahn, J.M, London, R.E. | Deposit date: | 2013-05-17 | Release date: | 2014-08-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.677 Å) | Cite: | Selective unfolding of one Ribonuclease H domain of HIV reverse transcriptase is linked to homodimer formation. Nucleic Acids Res., 42, 2014
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5DZM
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3K75
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3K77
| X-ray crystal structure of XRCC1 | Descriptor: | DNA repair protein XRCC1 | Authors: | Cuneo, M.J, London, R.E. | Deposit date: | 2009-10-12 | Release date: | 2010-04-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.597 Å) | Cite: | Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity. Proc.Natl.Acad.Sci.USA, 107, 2010
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3LQC
| X-ray crystal structure of oxidized XRCC1 bound to DNA pol beta Palm thumb domain | Descriptor: | CARBONATE ION, DNA polymerase beta, DNA repair protein XRCC1, ... | Authors: | Cuneo, M.J, Krahn, J.M, London, R.E. | Deposit date: | 2010-02-09 | Release date: | 2010-04-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.349 Å) | Cite: | Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity. Proc.Natl.Acad.Sci.USA, 107, 2010
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4XDS
| Deoxyguanosinetriphosphate Triphosphohydrolase from Escherichia coli with Nickel | Descriptor: | Deoxyguanosinetriphosphate triphosphohydrolase, NICKEL (II) ION, SULFATE ION | Authors: | Singh, D, Gawel, D, Itsko, M, Krahn, J.M, London, R.E, Schaaper, R.M. | Deposit date: | 2014-12-19 | Release date: | 2015-02-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.354 Å) | Cite: | Structure of Escherichia coli dGTP Triphosphohydrolase: A HEXAMERIC ENZYME WITH DNA EFFECTOR MOLECULES. J.Biol.Chem., 290, 2015
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4X9E
| DEOXYGUANOSINETRIPHOSPHATE TRIPHOSPHOHYDROLASE from Escherichia coli with two DNA effector molecules | Descriptor: | Deoxyguanosinetriphosphate triphosphohydrolase, MAGNESIUM ION, RNA (5'-R(P*CP*CP*C)-3') | Authors: | Singh, D, Gawel, D, Itsko, M, Krahn, J.M, London, R.E, Schaaper, R.M. | Deposit date: | 2014-12-11 | Release date: | 2015-02-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of Escherichia coli dGTP Triphosphohydrolase: A HEXAMERIC ENZYME WITH DNA EFFECTOR MOLECULES. J.Biol.Chem., 290, 2015
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4ZCE
| Crystal Structure of the dust mite allergen Der p 23 from Dermatophagoides pteronyssinus | Descriptor: | 1,2-ETHANEDIOL, Dust mite allergen | Authors: | Pedersen, L.C, Mueller, G.A, Randall, T.A, Glesner, J, Perera, L, Edwards, L.L, Chapman, M.D, London, R.E, Pomes, A. | Deposit date: | 2015-04-15 | Release date: | 2015-11-25 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Serological, genomic and structural analyses of the major mite allergen Der p 23. Clin Exp Allergy, 46, 2016
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2IDO
| Structure of the E. coli Pol III epsilon-Hot proofreading complex | Descriptor: | 1,2-ETHANEDIOL, DNA polymerase III epsilon subunit, Hot protein, ... | Authors: | Kirby, T.W, Harvey, S, DeRose, E.F, Chalov, S, Chikova, A.K, Perrino, F.W, Schaaper, R.M, London, R.E, Pedersen, L.C. | Deposit date: | 2006-09-15 | Release date: | 2006-11-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the Escherichia coli DNA polymerase III epsilon-HOT proofreading complex. J.Biol.Chem., 281, 2006
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2KHX
| Drosha double-stranded RNA binding motif | Descriptor: | Ribonuclease 3 | Authors: | Mueller, G.A, Miller, M, Ghosh, M, DeRose, E.F, London, R.E, Hall, T. | Deposit date: | 2009-04-13 | Release date: | 2010-02-23 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the Drosha double-stranded RNA-binding domain. Silence, 1, 2010
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2HTF
| The solution structure of the BRCT domain from human polymerase reveals homology with the TdT BRCT domain | Descriptor: | DNA polymerase mu | Authors: | DeRose, E.F, Clarkson, M.W, Gilmore, S.A, Ramsden, D.A, Mueller, G.A, London, R.E, Lee, A.L. | Deposit date: | 2006-07-25 | Release date: | 2007-02-27 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of polymerase mu's BRCT Domain reveals an element essential for its role in nonhomologous end joining. Biochemistry, 46, 2007
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2JW5
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2L7D
| Ribonucleotide Perturbation of DNA Structure: Solution Structure of [d(CGC)r(G)d(AATTCGCG)]2 | Descriptor: | 5'-D(*CP*GP*C)-R(P*G)-D(P*AP*AP*TP*TP*CP*GP*CP*G)-3' | Authors: | DeRose, E.F, Perera, L, Murray, M.S, Kunkel, T.A, London, R.E. | Deposit date: | 2010-12-07 | Release date: | 2011-06-01 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the Dickerson DNA dodecamer containing a single ribonucleotide. Biochemistry, 51, 2012
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3OB4
| MBP-fusion protein of the major peanut allergen Ara h 2 | Descriptor: | CHLORIDE ION, Maltose ABC transporter periplasmic protein,Arah 2, SULFATE ION, ... | Authors: | Mueller, G.A, Gosavi, R.A, Moon, A.F, London, R.E, Pedersen, L.C. | Deposit date: | 2010-08-06 | Release date: | 2011-02-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.706 Å) | Cite: | Ara h 2: crystal structure and IgE binding distinguish two subpopulations of peanut allergic patients by epitope diversity. Allergy, 66, 2011
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3PC7
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3PC6
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3PC8
| X-ray crystal structure of the heterodimeric complex of XRCC1 and DNA ligase III-alpha BRCT domains. | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA ligase 3, DNA repair protein XRCC1, ... | Authors: | Cuneo, M.J, Krahn, J.M, London, R.E. | Deposit date: | 2010-10-21 | Release date: | 2011-06-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | The structural basis for partitioning of the XRCC1/DNA ligase III-{alpha} BRCT-mediated dimer complexes. Nucleic Acids Res., 39, 2011
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