3K75

X-ray crystal structure of reduced XRCC1 bound to DNA pol beta catalytic domain

Summary for 3K75

Entry DOI	10.2210/pdb3k75/pdb
Related	3K76 3K77
Descriptor	DNA repair protein XRCC1, DNA polymerase beta (2 entities in total)
Functional Keywords	allosteric disulfide, xrcc1, pol beta, dna damage, dna repair, nucleus, phosphoprotein, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, lyase, magnesium, metal-binding, methylation, nucleotidyltransferase, transferase, dna-binding protein, dna binding protein
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: P18887 P06766
Total number of polymer chains	4
Total formula weight	100793.28
Authors	Cuneo, M.J.,London, R.E. (deposition date: 2009-10-12, release date: 2010-04-28, Last modification date: 2024-02-21)
Primary citation	Cuneo, M.J.,London, R.E. Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity. Proc.Natl.Acad.Sci.USA, 107:6805-6810, 2010 Cited by PubMed: 20351257 DOI: 10.1073/pnas.0914077107 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.95 Å)

Structure validation