5W7X

Crystal Structure of FHA domain of human APLF in complex with XRCC1 bisphospho peptide

Summary for 5W7X

• Entry DOI: 10.2210/pdb5w7x/pdb
• Descriptor: Aprataxin and PNK-like factor, DNA repair protein XRCC1 (3 entities in total)
• Functional Keywords: scaffold protein, dna repair, nhej, protein binding
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus: Q8IW19 P18887
• Total number of polymer chains: 8
• Total formula weight: 52138.77

Authors

Pedersen, L.C.,Kim, K.,London, R.E. (deposition date: 2017-06-21, release date: 2018-05-02, Last modification date: 2023-10-04)

• Primary citation: Kim, K.,Pedersen, L.C.,Kirby, T.W.,DeRose, E.F.,London, R.E.; Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications.; Nucleic Acids Res., 45:12374-12387, 2017; PubMed: 29059378; DOI: 10.1093/nar/gkx941

Experimental method

X-RAY DIFFRACTION (2.005 Å)