5W7X
Crystal Structure of FHA domain of human APLF in complex with XRCC1 bisphospho peptide
Summary for 5W7X
Entry DOI | 10.2210/pdb5w7x/pdb |
Descriptor | Aprataxin and PNK-like factor, DNA repair protein XRCC1 (3 entities in total) |
Functional Keywords | scaffold protein, dna repair, nhej, protein binding |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus: Q8IW19 P18887 |
Total number of polymer chains | 8 |
Total formula weight | 52138.77 |
Authors | Pedersen, L.C.,Kim, K.,London, R.E. (deposition date: 2017-06-21, release date: 2018-05-02, Last modification date: 2023-10-04) |
Primary citation | Kim, K.,Pedersen, L.C.,Kirby, T.W.,DeRose, E.F.,London, R.E. Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications. Nucleic Acids Res., 45:12374-12387, 2017 Cited by PubMed: 29059378DOI: 10.1093/nar/gkx941 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.005 Å) |
Structure validation
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