4JRB

Structure of Cockroach Allergen Bla g 1 Tandem Repeat as a EGFP fusion

Summary for 4JRB

• Entry DOI: 10.2210/pdb4jrb/pdb
• Descriptor: Green fluorescent protein, CHLORIDE ION, (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, ... (5 entities in total)
• Functional Keywords: allergen, asthma, new fold, proposed lipid binding protein, lipid binding protein
• Biological source: Aequorea victoria (Jellyfish); More
• Total number of polymer chains: 1
• Total formula weight: 48582.76

Authors

Mueller, G.A.,Pedersen, L.C.,Lih, F.B.,Glesner, J.,Moon, A.F.,Chapman, M.D.,Tomer, K.,London, R.E. (deposition date: 2013-03-21, release date: 2013-07-24, Last modification date: 2024-10-16)

Primary citation

Mueller, G.A.,Pedersen, L.C.,Lih, F.B.,Glesner, J.,Moon, A.F.,Chapman, M.D.,Tomer, K.B.,London, R.E.,Pomes, A.
The novel structure of the cockroach allergen Bla g 1 has implications for allergenicity and exposure assessment.
J.Allergy Clin.Immunol., 132:1420-1426.e9, 2013

PubMed Abstract: Sensitization to cockroach allergens is a major risk factor for asthma. The cockroach allergen Bla g 1 has multiple repeats of approximately 100 amino acids, but the fold of the protein and its biological function are unknown.

PubMed: 23915714
DOI: 10.1016/j.jaci.2013.06.014

Experimental method

X-RAY DIFFRACTION (2.414 Å)