3PC7

X-ray crystal structure of the DNA ligase III-alpha BRCT domain.

Summary for 3PC7

• Entry DOI: 10.2210/pdb3pc7/pdb
• Related: 3PC6 3PC8 3QVG
• Descriptor: DNA ligase 3 (2 entities in total)
• Functional Keywords: dna repair, brct domain, protein:protein interactions, xrcc1 brct2 domain, dna binding protein, ligase
• Biological source: Homo sapiens (human)
• Cellular location: Isoform 1: Mitochondrion . Isoform 2: Mitochondrion . Isoform 3: Nucleus . Isoform 4: Nucleus : P49916
• Total number of polymer chains: 2
• Total formula weight: 20000.37

Authors

Cuneo, M.J.,Krahn, J.M.,London, R.E. (deposition date: 2010-10-21, release date: 2011-06-15, Last modification date: 2023-12-06)

• Primary citation: Cuneo, M.J.,Gabel, S.A.,Krahn, J.M.,Ricker, M.A.,London, R.E.; The structural basis for partitioning of the XRCC1/DNA ligase III-{alpha} BRCT-mediated dimer complexes.; Nucleic Acids Res., 39:7816-7827, 2011; PubMed: 21652643; DOI: 10.1093/nar/gkr419

Experimental method

X-RAY DIFFRACTION (1.65 Å)