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7JZV
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BU of 7jzv by Molmil
Cryo-EM structure of the BRCA1-UbcH5c/BARD1 E3-E2 module bound to a nucleosome
Descriptor: BRCA1,Ubiquitin-conjugating enzyme E2 D3, BRCA1-associated RING domain protein 1, Histone H2A type 2-A, ...
Authors:Witus, S.R, Burrell, A.L, Hansen, J.M, Farrell, D.P, Dimaio, F, Kollman, J.M, Klevit, R.E.
Deposit date:2020-09-02
Release date:2021-02-17
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1.
Nat.Struct.Mol.Biol., 28, 2021
2ADR
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BU of 2adr by Molmil
ADR1 DNA-BINDING DOMAIN FROM SACCHAROMYCES CEREVISIAE, NMR, 25 STRUCTURES
Descriptor: ADR1, ZINC ION
Authors:Bowers, P.M, Kleivt, R.E.
Deposit date:1998-03-20
Release date:1998-06-17
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:A folding transition and novel zinc finger accessory domain in the transcription factor ADR1.
Nat.Struct.Biol., 6, 1999
4UEY
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BU of 4uey by Molmil
Structure of the periplasmic domain PhoQ double mutant (W104C-A128C)
Descriptor: PHOQ PERIPLASMIC DOMAIN DOUBLE MUTANT
Authors:Sancho-Vaello, E, Hicks, K.G, Miller, S.I, Zeth, K.
Deposit date:2014-12-21
Release date:2015-06-24
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Acidic pH and divalent cation sensing by PhoQ are dispensable for systemic salmonellae virulence.
Elife, 4, 2015
6P5H
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BU of 6p5h by Molmil
Structure of MavC middle insertion domain
Descriptor: MavC
Authors:Negron Teron, K.I, Puvar, K, Iyer, S, Das, C.
Deposit date:2019-05-30
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination.
Nat Commun, 11, 2020
6P5B
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BU of 6p5b by Molmil
Crystal Structure of MavC in Complex with Ub-UbE2N
Descriptor: MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N
Authors:Puvar, K, Iyer, S, Negron Teron, K.I, Das, C.
Deposit date:2019-05-30
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination.
Nat Commun, 11, 2020
4JLR
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BU of 4jlr by Molmil
Crystal structure of a designed Respiratory Syncytial Virus Immunogen in complex with Motavizumab
Descriptor: Motavizumab Fab heavy chain, Motavizumab Fab light chain, PENTAETHYLENE GLYCOL, ...
Authors:Rupert, P.B, Correia, B, Schief, W, Strong, R.K.
Deposit date:2013-03-12
Release date:2014-02-05
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Proof of principle for epitope-focused vaccine design.
Nature, 507, 2014
6CYR
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BU of 6cyr by Molmil
Crystal structure of the UBE2A variant Q93E
Descriptor: Ubiquitin-conjugating enzyme E2 A
Authors:Ranzani, A.T, de Oliveira, J.F.
Deposit date:2018-04-06
Release date:2018-12-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanistic insights revealed by a UBE2A mutation linked to intellectual disability.
Nat. Chem. Biol., 15, 2019
6CYO
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BU of 6cyo by Molmil
Crystal structure of human UBE2A (RAD6A)
Descriptor: Ubiquitin-conjugating enzyme E2 A
Authors:Ranzani, A.T, de Oliveira, J.F.
Deposit date:2018-04-06
Release date:2018-12-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Mechanistic insights revealed by a UBE2A mutation linked to intellectual disability.
Nat. Chem. Biol., 15, 2019
1YAX
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BU of 1yax by Molmil
Cystal structure Analysis of S.typhimurium PhoQ sensor domain with Calcium
Descriptor: CALCIUM ION, Virulence sensor protein phoQ, sensor domain
Authors:Cho, U.S, Xu, W.
Deposit date:2004-12-17
Release date:2005-12-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Metal bridges between the PhoQ sensor domain and the membrane regulate transmembrane signaling.
J.Mol.Biol., 356, 2006
6ULH
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BU of 6ulh by Molmil
Structure of MavC in complex with its substrate in R3 spacegroup
Descriptor: LPG2147 (MavC), Ubiquitin, Ubiquitin-conjugating enzyme E2 N
Authors:Iyer, S, Puvar, K, Das, C.
Deposit date:2019-10-08
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.968 Å)
Cite:Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination.
Nat Commun, 11, 2020
6UMS
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BU of 6ums by Molmil
Crystal structure of MavC in complex with its substrate mimic in C222(1) space group
Descriptor: MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N
Authors:Iyer, S, Puvar, K, Das, C.
Deposit date:2019-10-10
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.344 Å)
Cite:Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination.
Nat Commun, 11, 2020
6UMP
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BU of 6ump by Molmil
Crystal structure of MavC in complex with substrate mimic in P65 space group
Descriptor: MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N
Authors:Puvar, K, Iyer, S, Luo, Z.Q, Das, C.
Deposit date:2019-10-10
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination.
Nat Commun, 11, 2020
4L8I
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BU of 4l8i by Molmil
Crystal structure of RSV epitope scaffold FFL_005
Descriptor: RSV epitope scaffold FFL_005
Authors:Jardine, J, Correnti, C, Holmes, M.A, Strong, R.K, Schief, W.R.
Deposit date:2013-06-17
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Proof of principle for epitope-focused vaccine design.
Nature, 507, 2014
4N9G
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BU of 4n9g by Molmil
Crystal Structure of a Computationally Designed RSV-Presenting Epitope Scaffold And Its Elicited Antibody 17HD9
Descriptor: Antibody 17HD9, Heavy Chain, Light Chain, ...
Authors:Carrico, C.T.D, Strong, R.K.
Deposit date:2013-10-21
Release date:2014-02-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Proof of principle for epitope-focused vaccine design.
Nature, 507, 2014
5UDH
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BU of 5udh by Molmil
HHARI/ARIH1-UBCH7~Ubiquitin
Descriptor: E3 ubiquitin-protein ligase ARIH1, Ubiquitin C variant, Ubiquitin-conjugating enzyme E2 L3, ...
Authors:Miller, D.J, Schulman, B.A.
Deposit date:2016-12-27
Release date:2017-06-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Structural Studies of HHARI/UbcH7Ub Reveal Unique E2Ub Conformational Restriction by RBR RING1.
Structure, 25, 2017
5UTG
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BU of 5utg by Molmil
Red abalone lysin F104A
Descriptor: Egg-lysin
Authors:Wilburn, D.B, Tuttle, L.M.
Deposit date:2017-02-14
Release date:2018-01-31
Last modified:2019-12-11
Method:SOLUTION NMR
Cite:Solution structure of sperm lysin yields novel insights into molecular dynamics of rapid protein evolution.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4DDI
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BU of 4ddi by Molmil
Crystal structure of human OTUB1/UbcH5b~Ub/Ub
Descriptor: Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin thioesterase OTUB1
Authors:Juang, Y.C, Sanches, M, Sicheri, F.
Deposit date:2012-01-18
Release date:2012-02-22
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.802 Å)
Cite:OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function.
Mol.Cell, 45, 2012
4DDG
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BU of 4ddg by Molmil
Crystal structure of human OTUB1/UbcH5b~Ub/Ub
Descriptor: Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin thioesterase OTUB1
Authors:Juang, Y.C, Sanches, M, Sicheri, F.
Deposit date:2012-01-18
Release date:2012-02-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.2987 Å)
Cite:OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function.
Mol.Cell, 45, 2012
6B7Q
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BU of 6b7q by Molmil
Crystal structure of Legionella effector protein sdeA (lpg2157) aa. 211-910
Descriptor: MERCURY (II) ION, SdeA
Authors:Mao, Y, Akturk, A, Wasilko, J.
Deposit date:2017-10-04
Release date:2018-04-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector.
Nature, 557, 2018
6B7M
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BU of 6b7m by Molmil
Crystal structure of Legionella effector sdeD (lpg2509) in complex with Ubiquitin
Descriptor: Polyubiquitin-C, SdeD (lpg2509)
Authors:Mao, Y, Akturk, A, Wasilko, J.
Deposit date:2017-10-04
Release date:2018-04-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector.
Nature, 557, 2018
6B7O
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BU of 6b7o by Molmil
Crystal structure of Legionella effector sdeD (lpg2509) H67A in complex with ADP-ribosylated Ubiquitin
Descriptor: Polyubiquitin-C, SdeD (lpg2509) H67A, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
Authors:Mao, Y, Akturk, A, Wasilko, J.
Deposit date:2017-10-04
Release date:2018-04-18
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector.
Nature, 557, 2018
6B7P
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BU of 6b7p by Molmil
Crystal structure of Legionella effector sdeD (lpg2509)
Descriptor: SdeD
Authors:Mao, Y, Akturk, A, Wasilko, J.
Deposit date:2017-10-04
Release date:2018-04-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector.
Nature, 557, 2018
6CF6
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BU of 6cf6 by Molmil
RNF146 TBM-Tankyrase ARC2-3 complex
Descriptor: RNF146, Tankyrase-1
Authors:Da Rosa, P.A, Xu, W.
Deposit date:2018-02-13
Release date:2018-04-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structural basis for tankyrase-RNF146 interaction reveals noncanonical tankyrase-binding motifs.
Protein Sci., 27, 2018
2KR4
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BU of 2kr4 by Molmil
U-box domain of the E3 Ubiquitin Ligase E4B
Descriptor: Ubiquitin conjugation factor E4 B
Authors:Nordquist, K, Soss, S, Chazin, W.
Deposit date:2009-12-03
Release date:2010-01-26
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structural and functional characterization of the monomeric U-box domain from E4B.
Biochemistry, 49, 2010
1OPD
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BU of 1opd by Molmil
HISTIDINE-CONTAINING PROTEIN (HPR), MUTANT WITH SER 46 REPLACED BY ASP (S46D)
Descriptor: HISTIDINE-CONTAINING PROTEIN, SULFATE ION
Authors:Napper, S, Delbaere, L, Waygood, B.
Deposit date:1996-08-01
Release date:1997-08-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Mutation of serine-46 to aspartate in the histidine-containing protein of Escherichia coli mimics the inactivation by phosphorylation of serine-46 in HPrs from gram-positive bacteria.
Biochemistry, 35, 1996

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