6CYR

Crystal structure of the UBE2A variant Q93E

Summary for 6CYR

Entry DOI	10.2210/pdb6cyr/pdb
Related	6CYO
Descriptor	Ubiquitin-conjugating enzyme E2 A (2 entities in total)
Functional Keywords	ubiquitin-conjungating enzyme e2 a, q93e variant, ligase, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	17615.63
Authors	Ranzani, A.T.,de Oliveira, J.F. (deposition date: 2018-04-06, release date: 2018-12-12, Last modification date: 2023-10-04)
Primary citation	de Oliveira, J.F.,do Prado, P.F.V.,da Costa, S.S.,Sforca, M.L.,Canateli, C.,Ranzani, A.T.,Maschietto, M.,de Oliveira, P.S.L.,Otto, P.A.,Klevit, R.E.,Krepischi, A.C.V.,Rosenberg, C.,Franchini, K.G. Mechanistic insights revealed by a UBE2A mutation linked to intellectual disability. Nat. Chem. Biol., 15:62-70, 2019 Cited by PubMed: 30531907 DOI: 10.1038/s41589-018-0177-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation