3MB8
| Crystal structure of purine nucleoside phosphorylase from toxoplasma gondii in complex with immucillin-H | 分子名称: | 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, GLYCEROL, PHOSPHATE ION, ... | 著者 | Ho, M, Almo, S.C, Schramm, V.L. | 登録日 | 2010-03-25 | 公開日 | 2011-04-06 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Inhibition and Structure of Toxoplasma gondii Purine Nucleoside Phosphorylase. Eukaryot Cell, 13, 2014
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5E8Y
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5E8V
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5E8X
| TGF-BETA RECEPTOR TYPE 1 KINASE DOMAIN (T204D,I211V,Y249F,S280T, Y282F,S287N,A350C,L352F) IN COMPLEX WITH STAUROSPORINE | 分子名称: | GLYCEROL, STAUROSPORINE, TGF-beta receptor type-1 | 著者 | Sheriff, S. | 登録日 | 2015-10-14 | 公開日 | 2016-05-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Crystal structures of apo and inhibitor-bound TGF beta R2 kinase domain: insights into TGF beta R isoform selectivity. Acta Crystallogr D Struct Biol, 72, 2016
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5E8W
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5E8U
| TGF-BETA RECEPTOR TYPE 1 KINASE DOMAIN (T204D,I211V,Y249F,S280T, Y282F,S287N,A350C,L352F) | 分子名称: | GLYCEROL, TGF-beta receptor type-1 | 著者 | Sheriff, S. | 登録日 | 2015-10-14 | 公開日 | 2016-05-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Crystal structures of apo and inhibitor-bound TGF beta R2 kinase domain: insights into TGF beta R isoform selectivity. Acta Crystallogr D Struct Biol, 72, 2016
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5E91
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5E90
| TGF-BETA RECEPTOR TYPE 1 KINASE DOMAIN (T204D,I211V,Y249F, S280T,Y282F,S287N,A350C,L352F) IN COMPLEX WITH 3-AMINO-6- [4-(2-HYDROXYETHYL)PHENYL]-N-[4-(MORPHOLIN-4-YL)PYRIDIN-3-YL]PYRAZINE-2-CARBOXAMIDE | 分子名称: | 3-amino-6-[4-(2-hydroxyethyl)phenyl]-N-[4-(morpholin-4-yl)pyridin-3-yl]pyrazine-2-carboxamide, TGF-beta receptor type-1 | 著者 | Sheriff, S. | 登録日 | 2015-10-14 | 公開日 | 2016-05-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structures of apo and inhibitor-bound TGF beta R2 kinase domain: insights into TGF beta R isoform selectivity. Acta Crystallogr D Struct Biol, 72, 2016
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5E8T
| TGF-BETA RECEPTOR TYPE 1 KINASE DOMAIN (T204D) | 分子名称: | GLYCEROL, TGF-beta receptor type-1 | 著者 | Sheriff, S. | 登録日 | 2015-10-14 | 公開日 | 2016-05-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structures of apo and inhibitor-bound TGF beta R2 kinase domain: insights into TGF beta R isoform selectivity. Acta Crystallogr D Struct Biol, 72, 2016
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5E92
| TGF-BETA RECEPTOR TYPE 2 KINASE DOMAIN (E431A,R433A,E485A,K488A,R493A,R495A) IN COMPLEX WITH AMPPNP | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, TGF-beta receptor type-2 | 著者 | Sheriff, S. | 登録日 | 2015-10-14 | 公開日 | 2016-05-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Crystal structures of apo and inhibitor-bound TGF beta R2 kinase domain: insights into TGF beta R isoform selectivity. Acta Crystallogr D Struct Biol, 72, 2016
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5E8S
| TGF-BETA RECEPTOR TYPE 1 KINASE DOMAIN (WT) | 分子名称: | TGF-beta receptor type-1 | 著者 | Sheriff, S. | 登録日 | 2015-10-14 | 公開日 | 2016-05-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Crystal structures of apo and inhibitor-bound TGF beta R2 kinase domain: insights into TGF beta R isoform selectivity. Acta Crystallogr D Struct Biol, 72, 2016
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5E8Z
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6L18
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3EWC
| Crystal Structure of adenosine deaminase from Plasmodial vivax in complex with MT-coformycin | 分子名称: | (8R)-3-(5-S-methyl-5-thio-beta-D-ribofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol, Adenosine deaminase, ZINC ION | 著者 | Schramm, V.L, Almo, S.C, Cassera, M.B, Ho, M.C. | 登録日 | 2008-10-14 | 公開日 | 2009-09-22 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Structural and metabolic specificity of methylthiocoformycin for malarial adenosine deaminases. Biochemistry, 48, 2009
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3EWD
| Crystal structure of adenosine deaminase mutant (delta Asp172) from Plasmodium vivax in complex with MT-coformycin | 分子名称: | (8R)-3-(5-S-methyl-5-thio-beta-D-ribofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol, Adenosine deaminase, ZINC ION | 著者 | Schramm, V.L, Almo, S.C, Cassera, M.B, Ho, M.C. | 登録日 | 2008-10-14 | 公開日 | 2009-09-22 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and metabolic specificity of methylthiocoformycin for malarial adenosine deaminases. Biochemistry, 48, 2009
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3FOW
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6NE5
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1RR6
| Structure of human purine nucleoside phosphorylase in complex with Immucillin-H and phosphate | 分子名称: | 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, PHOSPHATE ION, Purine nucleoside phosphorylase | 著者 | Shi, W, Lewandowicz, A, Tyler, P.C, Furneaux, R.H, Almo, S.C, Schramm, V.L. | 登録日 | 2003-12-08 | 公開日 | 2005-02-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function. J.Biol.Chem., 279, 2004
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7UM4
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7UM6
| CryoEM structure of Go-coupled 5-HT5AR in complex with Lisuride | 分子名称: | 5-hydroxytryptamine receptor 5A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhang, S, Fay, J.F, Roth, B.L. | 登録日 | 2022-04-06 | 公開日 | 2022-07-20 | 最終更新日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | 主引用文献 | Inactive and active state structures template selective tools for the human 5-HT 5A receptor. Nat.Struct.Mol.Biol., 29, 2022
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7UM5
| CryoEM structure of Go-coupled 5-HT5AR in complex with 5-CT | 分子名称: | 3-(2-azanylethyl)-1H-indole-5-carboxamide, 5-hydroxytryptamine receptor 5A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Zhang, S, Fay, J.F, Roth, B.L. | 登録日 | 2022-04-06 | 公開日 | 2022-07-20 | 最終更新日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | 主引用文献 | Inactive and active state structures template selective tools for the human 5-HT 5A receptor. Nat.Struct.Mol.Biol., 29, 2022
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7UM7
| CryoEM structure of Go-coupled 5-HT5AR in complex with Methylergometrine | 分子名称: | (8beta)-N-[(2S)-1-hydroxybutan-2-yl]-6-methyl-9,10-didehydroergoline-8-carboxamide, 5-hydroxytryptamine receptor 5A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Zhang, S, Fay, J.F, Roth, B.L. | 登録日 | 2022-04-06 | 公開日 | 2022-07-20 | 最終更新日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | 主引用文献 | Inactive and active state structures template selective tools for the human 5-HT 5A receptor. Nat.Struct.Mol.Biol., 29, 2022
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7UU4
| Crystal structure of APOBEC3G complex with ssRNA | 分子名称: | DNA dC->dU-editing enzyme APOBEC-3G, RNA (5'-R(P*UP*AP*AP*UP*UP*U)-3'), SULFATE ION, ... | 著者 | Yang, H, Li, S, Chen, X.S. | 登録日 | 2022-04-28 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis of sequence-specific RNA recognition by the antiviral factor APOBEC3G. Nat Commun, 13, 2022
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7UU3
| Crystal structure of APOBEC3G complex with 3'overhangs RNA-Complex | 分子名称: | DNA dC->dU-editing enzyme APOBEC-3G, RNA (5'-R(*CP*CP*CP*AP*CP*GP*GP*GP*AP*AP*U)-3'), RNA (5'-R(*CP*CP*CP*GP*UP*GP*GP*GP*AP*AP*U)-3'), ... | 著者 | Yang, H, Li, S, Chen, X.S. | 登録日 | 2022-04-28 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.099 Å) | 主引用文献 | Structural basis of sequence-specific RNA recognition by the antiviral factor APOBEC3G. Nat Commun, 13, 2022
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7UU5
| Crystal structure of APOBEC3G complex with 5'-Overhang dsRNA | 分子名称: | DNA dC->dU-editing enzyme APOBEC-3G, RNA (5'-R(P*UP*AP*AP*CP*CP*GP*CP*AP*GP*CP*G)-3'), RNA (5'-R(P*UP*AP*AP*CP*GP*CP*UP*GP*CP*GP*G)-3'), ... | 著者 | Yang, H, Li, S, Chen, X.S. | 登録日 | 2022-04-28 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis of sequence-specific RNA recognition by the antiviral factor APOBEC3G. Nat Commun, 13, 2022
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