3EWD
Crystal structure of adenosine deaminase mutant (delta Asp172) from Plasmodium vivax in complex with MT-coformycin
Summary for 3EWD
Entry DOI | 10.2210/pdb3ewd/pdb |
Related | 3EWC |
Descriptor | Adenosine deaminase, ZINC ION, (8R)-3-(5-S-methyl-5-thio-beta-D-ribofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol, ... (4 entities in total) |
Functional Keywords | adenosine deaminase, mt-coformycin, methylthio-coformycin, hydrolase |
Biological source | Plasmodium vivax |
Total number of polymer chains | 1 |
Total formula weight | 43119.89 |
Authors | Schramm, V.L.,Almo, S.C.,Cassera, M.B.,Ho, M.C. (deposition date: 2008-10-14, release date: 2009-09-22, Last modification date: 2023-12-27) |
Primary citation | Ho, M.C.,Cassera, M.B.,Madrid, D.C.,Ting, L.M.,Tyler, P.C.,Kim, K.,Almo, S.C.,Schramm, V.L. Structural and metabolic specificity of methylthiocoformycin for malarial adenosine deaminases. Biochemistry, 48:9618-9626, 2009 Cited by PubMed: 19728741DOI: 10.1021/bi9012484 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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