5GRX
| Crystal structure of disulfide-bonded diabody | 分子名称: | diabody protein | 著者 | Kim, J.H, Song, D.H, Youn, S.J, Kim, J.W, Cho, G, Lee, H, Lee, J.O. | 登録日 | 2016-08-12 | 公開日 | 2016-10-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | 主引用文献 | Crystal structure of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface. Sci Rep, 6, 2016
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7V5C
| Cryo-EM structure of the mouse ABCB9 (ADP.BeF3-bound) | 分子名称: | ABC-type oligopeptide transporter ABCB9, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | 著者 | Park, J.G, Kim, S, Jang, E, Choi, S.H, Han, H, Kim, J.W, Ju, S, Min, D.S, Jin, M.S. | 登録日 | 2021-08-17 | 公開日 | 2022-10-19 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The lysosomal transporter TAPL has a dual role as peptide translocator and phosphatidylserine floppase. Nat Commun, 13, 2022
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7V5D
| Cryo-EM structure of the mouse ABCB9 (PG-bound) | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, ABC-type oligopeptide transporter ABCB9 | 著者 | Park, J.G, Kim, S, Jang, E, Choi, S.H, Han, H, Ju, S, Kim, J.W, Min, D.S, Jin, M.S. | 登録日 | 2021-08-17 | 公開日 | 2022-10-19 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | The lysosomal transporter TAPL has a dual role as peptide translocator and phosphatidylserine floppase. Nat Commun, 13, 2022
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7VFI
| Cryo-EM structure of the mouse TAPL (9mer-peptide bound) | 分子名称: | ABC-type oligopeptide transporter ABCB9, ARG-ARG-TYR-GLN-LYS-SER-THR-GLU-LEU, CHOLESTEROL HEMISUCCINATE | 著者 | Park, J.G, Kim, S, Jang, E, Choi, S.H, Han, H, Kim, J.W, Ju, S, Min, D.S, Jin, M.S. | 登録日 | 2021-09-13 | 公開日 | 2022-10-19 | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | 主引用文献 | The lysosomal transporter TAPL has a dual role as peptide translocator and phosphatidylserine floppase. Nat Commun, 13, 2022
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7YC5
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7CM4
| Crystal Structure of COVID-19 virus spike receptor-binding domain complexed with a neutralizing antibody CT-P59 | 分子名称: | 1,2-ETHANEDIOL, IgG heavy chain, IgG light chain, ... | 著者 | Kim, Y.G, Jeong, J.H, Bae, J.S, Lee, J. | 登録日 | 2020-07-24 | 公開日 | 2021-01-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike protein. Nat Commun, 12, 2021
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7CT6
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7EEW
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8GTI
| Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-C205 by XFEL | 分子名称: | 8-(4-bromanyl-2,6-dimethoxy-phenyl)-~{N}-butyl-~{N}-(cyclopropylmethyl)-2,7-dimethyl-pyrazolo[1,5-a][1,3,5]triazin-4-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1, ... | 著者 | Cho, H.S, Kim, H. | 登録日 | 2022-09-08 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser. Exp.Mol.Med., 55, 2023
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8GTM
| Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-C203 by XFEL | 分子名称: | 7-(4-bromanyl-2,6-dimethoxy-phenyl)-4,8-dimethyl-~{N},~{N}-bis[4,4,4-tris(fluoranyl)butyl]-1$l^{4},3,5,9-tetrazabicyclo[4.3.0]nona-1(6),2,4,8-tetraen-2-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1 | 著者 | Cho, H.S, Kim, H. | 登録日 | 2022-09-08 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser. Exp.Mol.Med., 55, 2023
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8GTG
| Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-I-152 by XFEL | 分子名称: | 8-(4-bromanyl-2,6-dimethoxy-phenyl)-~{N},~{N}-bis(2-methoxyethyl)-2,7-dimethyl-pyrazolo[1,5-a][1,3,5]triazin-4-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1 | 著者 | Cho, H.S, Kim, H. | 登録日 | 2022-09-08 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser. Exp.Mol.Med., 55, 2023
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8I08
| Crystal structure of Escherichia coli glyoxylate carboligase quadruple mutant | 分子名称: | 2,3-DIMETHOXY-5-METHYL-1,4-BENZOQUINONE, FLAVIN-ADENINE DINUCLEOTIDE, Glyoxylate carboligase, ... | 著者 | Kim, J.H, Kim, J.S. | 登録日 | 2023-01-10 | 公開日 | 2023-11-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Engineering of two thiamine diphosphate-dependent enzymes for the regioselective condensation of C1-formaldehyde into C4-erythrulose. Int.J.Biol.Macromol., 253, 2023
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8I07
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8I01
| Crystal structure of Escherichia coli glyoxylate carboligase | 分子名称: | 2,3-DIMETHOXY-5-METHYL-1,4-BENZOQUINONE, FLAVIN-ADENINE DINUCLEOTIDE, Glyoxylate carboligase, ... | 著者 | Kim, J.H, Kim, J.S. | 登録日 | 2023-01-10 | 公開日 | 2023-11-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Engineering of two thiamine diphosphate-dependent enzymes for the regioselective condensation of C1-formaldehyde into C4-erythrulose. Int.J.Biol.Macromol., 253, 2023
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8I05
| Crystal structure of Escherichia coli glyoxylate carboligase double mutant | 分子名称: | 2,3-DIMETHOXY-5-METHYL-1,4-BENZOQUINONE, FLAVIN-ADENINE DINUCLEOTIDE, Glyoxylate carboligase, ... | 著者 | Kim, J.H, Kim, J.S. | 登録日 | 2023-01-10 | 公開日 | 2023-11-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Engineering of two thiamine diphosphate-dependent enzymes for the regioselective condensation of C1-formaldehyde into C4-erythrulose. Int.J.Biol.Macromol., 253, 2023
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6JDK
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2XMQ
| Crystal structure of human NDRG2 protein provides insight into its role as a tumor suppressor | 分子名称: | ACETATE ION, PROTEIN NDRG2 | 著者 | Hwang, J, Kim, Y, Lee, H, Kim, M.H. | 登録日 | 2010-07-29 | 公開日 | 2011-01-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Crystal Structure of Human Ndrg2 Protein Provides Insight Into its Role as a Tumor Suppressor. J.Biol.Chem., 286, 2011
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2XMR
| Crystal structure of human NDRG2 protein provides insight into its role as a tumor suppressor | 分子名称: | ACETATE ION, CALCIUM ION, GLYCEROL, ... | 著者 | Hwang, J, Kim, Y, Lee, H, Kim, M.H. | 登録日 | 2010-07-29 | 公開日 | 2011-01-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Human Ndrg2 Protein Provides Insight Into its Role as a Tumor Suppressor. J.Biol.Chem., 286, 2011
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2XMS
| Crystal structure of human NDRG2 protein provides insight into its role as a tumor suppressor | 分子名称: | CHLORIDE ION, IMIDAZOLE, PROTEIN NDRG2 | 著者 | Hwang, J, Kim, Y, Lee, H, Kim, M.H. | 登録日 | 2010-07-29 | 公開日 | 2011-01-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal Structure of Human Ndrg2 Protein Provides Insight Into its Role as a Tumor Suppressor. J.Biol.Chem., 286, 2011
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2QMQ
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5GRU
| Structure of mono-specific diabody | 分子名称: | Maltose-binding periplasmic protein, diabody protein | 著者 | Kim, J.H, Song, D.H, Youn, S.J, Cho, G, Lee, H, Lee, J.O. | 登録日 | 2016-08-12 | 公開日 | 2016-10-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.955 Å) | 主引用文献 | Crystal structure of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface. Sci Rep, 6, 2016
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6KMA
| Crystal structure of SucA with glycolaldehyde-1-13C from Vibrio vulnificus | 分子名称: | 2-oxidanylethanal, CALCIUM ION, HEXAETHYLENE GLYCOL, ... | 著者 | Seo, P.W, Kim, J.S. | 登録日 | 2019-07-31 | 公開日 | 2020-08-05 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.282 Å) | 主引用文献 | Understanding the molecular properties of the E1 subunit (SucA) of alpha-ketoglutarate dehydrogenase complex from Vibrio vulnificus for the enantioselective ligation of acetaldehydes into (R)-acetoin. Catalysis Science And Technology, 2020
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6KM9
| Crystal structure of SucA from Vibrio vulnificus | 分子名称: | CALCIUM ION, HEXAETHYLENE GLYCOL, MAGNESIUM ION, ... | 著者 | Seo, P.W, Kim, J.S. | 登録日 | 2019-07-31 | 公開日 | 2020-08-05 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.724 Å) | 主引用文献 | Understanding the molecular properties of the E1 subunit (SucA) of alpha-ketoglutarate dehydrogenase complex from Vibrio vulnificus for the enantioselective ligation of acetaldehydes into (R)-acetoin. Catalysis Science And Technology, 2020
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1SMA
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5Y7K
| Crystal structure of human DPP4 in complex with inhibitor1 | 分子名称: | (R)-4-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-3-(tert-butoxymethyl)piperazine-2-one, Dipeptidyl peptidase 4 | 著者 | Lee, H.K, Kim, E.E. | 登録日 | 2017-08-17 | 公開日 | 2019-03-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.512 Å) | 主引用文献 | Unique binding mode of Evogliptin with human dipeptidyl peptidase IV. Biochem.Biophys.Res.Commun., 494, 2017
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