2XMR

Crystal structure of human NDRG2 protein provides insight into its role as a tumor suppressor

Summary for 2XMR

Related2XMS 2XMQ
DescriptorPROTEIN NDRG2, CALCIUM ION, ACETATE ION, ... (5 entities in total)
Functional Keywordssignaling protein, ndrg family
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm Q9UN36
Total number of polymer chains3
Total molecular weight94157.51
Authors
Hwang, J.,Kim, Y.,Lee, H.,Kim, M.H. (deposition date: 2010-07-29, release date: 2011-01-19, Last modification date: 2011-08-31)
Primary citation
Hwang, J.,Kim, Y.,Kang, H.B.,Jaroszewski, L.,Deacon, A.,Lee, H.,Choi, W.C.,Kim, K.J.,Kim, C.H.,Kang, B.S.,Lee, J.O.,Oh, T.K.,Kim, J.W.,Wilson, I.A.,Kim, M.H.
Crystal Structure of Human Ndrg2 Protein Provides Insight Into its Role as a Tumor Suppressor.
J.Biol.Chem., 286:12450-, 2011
PubMed: 21247902 (PDB entries with the same primary citation)
DOI: 10.1074/JBC.M110.170803
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.247402.1%12.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution