2XMR
Crystal structure of human NDRG2 protein provides insight into its role as a tumor suppressor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | PROTEIN NDRG2 | polymer | 281 | 31221.3 | 3 | UniProt (Q9UN36) Pfam (PF03096) In PDB | HOMO SAPIENS (HUMAN) | NDRG2 |
2 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
3 | A, B, C | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
4 | A, B, C | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
5 | water | water | 18.0 | 399 | Chemie (HOH) |
Sequence modifications
A, B, C: 24 - 304 (UniProt: Q9UN36)
PDB | External Database | Details |
---|---|---|
Ala 45 | Lys 45 | engineered mutation |
Ala 47 | Lys 47 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 93664.0 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 493.5 | |
All* | Total formula weight | 94157.5 |