Crystal structure of a n-myc downstream regulated 2 protein (ndrg2, syld, ndr2, ai182517, au040374) from mus musculus at 1.70 A resolution

Summary for 2QMQ

DescriptorProtein NDRG2, MAGNESIUM ION, BENZOIC ACID, ... (5 entities in total)
Functional Keywordsalpha/beta-hydrolases fold, ndr family, developmental protein, differentiation, neurogenesis, phosphorylation, regulatory protein, structural genomics, joint center for structural genomics, jcsg, protein structure initiative, psi-2, signaling protein
Biological sourceMus musculus (house mouse)
Total number of polymer chains1
Total molecular weight32595.41
Joint Center for Structural Genomics (JCSG) (deposition date: 2007-07-16, release date: 2007-09-04, Last modification date: 2019-07-24)
Primary citation
Hwang, J.,Kim, Y.,Kang, H.B.,Jaroszewski, L.,Deacon, A.M.,Lee, H.,Choi, W.C.,Kim, K.J.,Kim, C.H.,Kang, B.S.,Lee, J.O.,Oh, T.K.,Kim, J.W.,Wilson, I.A.,Kim, M.H.
Crystal structure of the human N-Myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor.
J.Biol.Chem., 286:12450-12460, 2011
PubMed: 21247902 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M110.170803
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.193300 1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution