Crystal structure of human NDRG2 protein provides insight into its role as a tumor suppressor

Summary for 2XMS

Related2XMR 2XMQ
DescriptorPROTEIN NDRG2, CHLORIDE ION, IMIDAZOLE, ... (4 entities in total)
Functional Keywordssignaling protein, ndrg family
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm Q9UN36
Total number of polymer chains1
Total molecular weight31579.15
Hwang, J.,Kim, Y.,Lee, H.,Kim, M.H. (deposition date: 2010-07-29, release date: 2011-01-19, Last modification date: 2011-08-31)
Primary citation
Hwang, J.,Kim, Y.,Kang, H.B.,Jaroszewski, L.,Deacon, A.,Lee, H.,Choi, W.C.,Kim, K.J.,Kim, C.H.,Kang, B.S.,Lee, J.O.,Oh, T.K.,Kim, J.W.,Wilson, I.A.,Kim, M.H.
Crystal Structure of Human Ndrg2 Protein Provides Insight Into its Role as a Tumor Suppressor.
J.Biol.Chem., 286:12450-, 2011
PubMed: 21247902 (PDB entries with the same primary citation)
DOI: 10.1074/JBC.M110.170803
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.243303.3%19.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload