4DZU
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![BU of 4dzu by Molmil](/molmil-images/mine/4dzu) | Complex of 3-alpha bound to gp41-5 | Descriptor: | 3-alpha, GLYCEROL, gp41-5 | Authors: | Johnson, L.M, Mortenson, D.E, Yun, H.G, Horne, W.S, Ketas, T.J, Lu, M, Moore, J.P, Gellman, S.H. | Deposit date: | 2012-03-01 | Release date: | 2012-05-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Enhancement of alpha-helix mimicry by an alpha / beta-peptide foldamer via incorporation of a dense ionic side-chain array. J.Am.Chem.Soc., 134, 2012
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4DZV
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![BU of 4dzv by Molmil](/molmil-images/mine/4dzv) | Complex of 4-alpha/beta bound to gp41-5 | Descriptor: | 4-alpha/beta, GLYCEROL, gp41-5 | Authors: | Johnson, L.M, Mortenson, D.E, Yun, H.G, Horne, W.S, Ketas, T.J, Lu, M, Moore, J.P, Gellman, S.H. | Deposit date: | 2012-03-01 | Release date: | 2012-05-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Enhancement of alpha-helix mimicry by an alpha / beta-peptide foldamer via incorporation of a dense ionic side-chain array. J.Am.Chem.Soc., 134, 2012
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3O43
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![BU of 3o43 by Molmil](/molmil-images/mine/3o43) | |
3O40
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![BU of 3o40 by Molmil](/molmil-images/mine/3o40) | Complex of a chimeric alpha/beta-peptide based on the gp41 CHR domain bound to gp41-5 | Descriptor: | CHLORIDE ION, GLYCEROL, NONAETHYLENE GLYCOL, ... | Authors: | Horne, W.S, Johnson, L.M, Gellman, S.H. | Deposit date: | 2010-07-26 | Release date: | 2011-07-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Broad Distribution of Energetically Important Contacts across an Extended Protein Interface. J.Am.Chem.Soc., 133, 2011
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3O3Z
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![BU of 3o3z by Molmil](/molmil-images/mine/3o3z) | |
3O3X
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![BU of 3o3x by Molmil](/molmil-images/mine/3o3x) | Crystal structure of gp41-5, a single-chain 5-helix-bundle based on HIV gp41 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ISOPROPYL ALCOHOL, gp41-5 | Authors: | Horne, W.S, Johnson, L.M, Gellman, S.H. | Deposit date: | 2010-07-26 | Release date: | 2011-07-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Broad Distribution of Energetically Important Contacts across an Extended Protein Interface. J.Am.Chem.Soc., 133, 2011
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3O42
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3O3Y
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![BU of 3o3y by Molmil](/molmil-images/mine/3o3y) | |
3G7A
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![BU of 3g7a by Molmil](/molmil-images/mine/3g7a) | HIV gp41 six-helix bundle composed of a chimeric alpha+alpha/beta-peptide analogue of the CHR domain in complex with an NHR domain alpha-peptide | Descriptor: | ACETYL GROUP, Chimeric alpha+alpha/beta-peptide analogue of the HIV gp41 CHR domain, Envelope glycoprotein gp160, ... | Authors: | Horne, W.S, Johnson, L.M, Gellman, S.H. | Deposit date: | 2009-02-09 | Release date: | 2009-10-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers Proc.Natl.Acad.Sci.USA, 106, 2009
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4NJ5
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![BU of 4nj5 by Molmil](/molmil-images/mine/4nj5) | Crystal structure of SUVH9 | Descriptor: | Probable histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH9, ZINC ION | Authors: | Du, J, Patel, D.J. | Deposit date: | 2013-11-08 | Release date: | 2014-01-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | SRA- and SET-domain-containing proteins link RNA polymerase V occupancy to DNA methylation. Nature, 507, 2014
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4ZNN
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![BU of 4znn by Molmil](/molmil-images/mine/4znn) | MicroED structure of the segment, GVVHGVTTVA, from the A53T familial mutant of Parkinson's disease protein, alpha-synuclein residues 47-56 | Descriptor: | Alpha-synuclein | Authors: | Rodriguez, J.A, Ivanova, M, Sawaya, M.R, Cascio, D, Reyes, F, Shi, D, Johnson, L, Guenther, E, Sangwan, S, Hattne, J, Nannenga, B, Brewster, A.S, Messerschmidt, M, Boutet, S, Sauter, N.K, Gonen, T, Eisenberg, D.S. | Deposit date: | 2015-05-05 | Release date: | 2015-09-09 | Last modified: | 2024-03-06 | Method: | ELECTRON CRYSTALLOGRAPHY (1.41 Å) | Cite: | Structure of the toxic core of alpha-synuclein from invisible crystals. Nature, 525, 2015
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4RIL
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![BU of 4ril by Molmil](/molmil-images/mine/4ril) | Structure of the amyloid forming segment, GAVVTGVTAVA, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 68-78, determined by electron diffraction | Descriptor: | Alpha-synuclein | Authors: | Rodriguez, J.A, Ivanova, M, Sawaya, M.R, Cascio, D, Reyes, F, Shi, D, Johnson, L, Guenther, E, Sangwan, S, Hattne, J, Nannenga, B, Brewster, A.S, Messerschmidt, M, Boutet, S, Sauter, N.K, Gonen, T, Eisenberg, D.S. | Deposit date: | 2014-10-06 | Release date: | 2015-08-26 | Last modified: | 2023-09-20 | Method: | ELECTRON CRYSTALLOGRAPHY (1.43 Å) | Cite: | Structure of the toxic core of alpha-synuclein from invisible crystals. Nature, 525, 2015
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4QEP
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![BU of 4qep by Molmil](/molmil-images/mine/4qep) | crystal structure of KRYPTONITE in complex with mCHG DNA and SAH | Descriptor: | DNA (5'-D(*AP*CP*TP*GP*CP*TP*GP*AP*GP*TP*AP*CP*CP*AP*T)-3'), DNA (5'-D(*GP*GP*TP*AP*CP*TP*(5CM)P*AP*GP*CP*AP*GP*TP*AP*T)-3'), Histone-lysine N-methyltransferase, ... | Authors: | Du, J, Li, S, Patel, D.J. | Deposit date: | 2014-05-17 | Release date: | 2014-07-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE. Mol.Cell, 55, 2014
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4QEN
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![BU of 4qen by Molmil](/molmil-images/mine/4qen) | crystal structure of KRYPTONITE in complex with mCHH DNA and SAH | Descriptor: | DNA (5'-D(*AP*CP*TP*GP*AP*TP*GP*AP*GP*TP*AP*CP*CP*AP*T)-3'), DNA (5'-D(*GP*GP*TP*AP*CP*TP*(5CM)P*AP*TP*CP*AP*GP*TP*AP*T)-3'), Histone-lysine N-methyltransferase, ... | Authors: | Du, J, Li, S, Patel, D.J. | Deposit date: | 2014-05-17 | Release date: | 2014-07-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.002 Å) | Cite: | Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE. Mol.Cell, 55, 2014
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4QEO
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![BU of 4qeo by Molmil](/molmil-images/mine/4qeo) | crystal structure of KRYPTONITE in complex with mCHH DNA, H3(1-15) peptide and SAH | Descriptor: | DNA 5'-ACTGATGAGTACCAT-3', DNA 5'-GGTACT(5CM)ATCAGTAT-3', Histone H3, ... | Authors: | Du, J, Li, S, Patel, D.J. | Deposit date: | 2014-05-17 | Release date: | 2014-07-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE. Mol.Cell, 55, 2014
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4NIO
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![BU of 4nio by Molmil](/molmil-images/mine/4nio) | |
4RIK
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![BU of 4rik by Molmil](/molmil-images/mine/4rik) | Amyloid forming segment, AVVTGVTAV, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 69-77 | Descriptor: | Alpha-synuclein | Authors: | Guenther, E.L, Sawaya, M.R, Ivanova, M, Eisenberg, D.S. | Deposit date: | 2014-10-06 | Release date: | 2015-08-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.854 Å) | Cite: | Structure of the toxic core of alpha-synuclein from invisible crystals. Nature, 525, 2015
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4TL5
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![BU of 4tl5 by Molmil](/molmil-images/mine/4tl5) | Crystal Structure of Human Transthyretin Ser85Pro Mutant | Descriptor: | CHLORIDE ION, SODIUM ION, Transthyretin | Authors: | Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S. | Deposit date: | 2014-05-28 | Release date: | 2015-10-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Uncovering the Mechanism of Aggregation of Human Transthyretin. J.Biol.Chem., 290, 2015
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4TKW
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4TL4
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![BU of 4tl4 by Molmil](/molmil-images/mine/4tl4) | |
4RP7
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4RP6
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![BU of 4rp6 by Molmil](/molmil-images/mine/4rp6) | |
4TLT
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![BU of 4tlt by Molmil](/molmil-images/mine/4tlt) | Crystal structure of human transthyretin | Descriptor: | MAGNESIUM ION, Transthyretin | Authors: | Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S. | Deposit date: | 2014-05-30 | Release date: | 2015-10-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Uncovering the Mechanism of Aggregation of Human Transthyretin. J.Biol.Chem., 290, 2015
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4TLK
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![BU of 4tlk by Molmil](/molmil-images/mine/4tlk) | Crystal Structure of Human Transthyretin Ser85Pro/Glu92Pro Mutant | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, SODIUM ION, ... | Authors: | Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S. | Deposit date: | 2014-05-30 | Release date: | 2015-10-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Uncovering the Mechanism of Aggregation of Human Transthyretin. J.Biol.Chem., 290, 2015
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4TM9
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![BU of 4tm9 by Molmil](/molmil-images/mine/4tm9) | |