3G7A
HIV gp41 six-helix bundle composed of a chimeric alpha+alpha/beta-peptide analogue of the CHR domain in complex with an NHR domain alpha-peptide
Summary for 3G7A
Entry DOI | 10.2210/pdb3g7a/pdb |
Related | 1AIK 3F4Y 3F50 |
Descriptor | Envelope glycoprotein gp160, Chimeric alpha+alpha/beta-peptide analogue of the HIV gp41 CHR domain, ACETYL GROUP, ... (5 entities in total) |
Functional Keywords | hiv, viral fusion, gp41, helix-bundle, alpha/beta-peptide, foldamer, aids, apoptosis, cell membrane, cleavage on pair of basic residues, envelope protein, fusion protein, glycoprotein, host-virus interaction, lipoprotein, membrane, palmitate, transmembrane, viral immunoevasion, virion, viral protein |
Cellular location | Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P04580 |
Total number of polymer chains | 2 |
Total formula weight | 9018.22 |
Authors | Horne, W.S.,Johnson, L.M.,Gellman, S.H. (deposition date: 2009-02-09, release date: 2009-10-20, Last modification date: 2023-11-15) |
Primary citation | Horne, W.S.,Johnson, L.M.,Ketas, T.J.,Klasse, P.J.,Lu, M.,Moore, J.P.,Gellman, S.H. Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers Proc.Natl.Acad.Sci.USA, 106:14751-14756, 2009 Cited by PubMed: 19706443DOI: 10.1073/pnas.0902663106 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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