3F4Y

HIV gp41 six-helix bundle containing a mutant CHR alpha-peptide sequence

Summary for 3F4Y

Entry DOI	10.2210/pdb3f4y/pdb
Related	1AIK 3F4Z 3F50
Descriptor	Envelope glycoprotein gp160, Mutant peptide derived from HIV gp41 CHR domain (3 entities in total)
Functional Keywords	helix bundle, aids, apoptosis, cell membrane, cleavage on pair of basic residues, coiled coil, envelope protein, fusion protein, glycoprotein, host-virus interaction, lipoprotein, membrane, palmitate, transmembrane, viral immunoevasion, virion, viral protein
Cellular location	Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P04580
Total number of polymer chains	6
Total formula weight	25787.30
Authors	Horne, W.S.,Gellman, S.H. (deposition date: 2008-11-03, release date: 2009-09-15, Last modification date: 2023-12-27)
Primary citation	Horne, W.S.,Johnson, L.M.,Ketas, T.J.,Klasse, P.J.,Lu, M.,Moore, J.P.,Gellman, S.H. Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers Proc.Natl.Acad.Sci.USA, 106:14751-14756, 2009 Cited by PubMed: 19706443 DOI: 10.1073/pnas.0902663106 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation