4IKM
 
 | | X-ray structure of CARD8 CARD domain | | 分子名称: | 1,2-ETHANEDIOL, IODIDE ION, Maltose-binding periplasmic protein, ... | | 著者 | Jin, T, Huang, M, Smith, P, Jiang, J, Xiao, T. | | 登録日 | 2012-12-26 | | 公開日 | 2013-05-08 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.4606 Å) | | 主引用文献 | The structure of the CARD8 caspase-recruitment domain suggests its association with the FIIND domain and procaspases through adjacent surfaces.
Acta Crystallogr.,Sect.F, 69, 2013
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4IW2
 | | HSA-glucose complex | | 分子名称: | D-glucose, PHOSPHATE ION, Serum albumin, ... | | 著者 | Wang, Y, Yu, H, Shi, X, Luo, Z, Huang, M. | | 登録日 | 2013-01-23 | | 公開日 | 2013-04-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Structural mechanism of ring-opening reaction of glucose by human serum albumin
J.Biol.Chem., 288, 2013
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4IRL
 | | X-ray structure of the CARD domain of zebrafish GBP-NLRP1 like protein | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Jin, T, Huang, M, Smith, P, Xiao, T. | | 登録日 | 2013-01-15 | | 公開日 | 2013-08-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | Structure of the caspase-recruitment domain from a zebrafish guanylate-binding protein.
Acta Crystallogr.,Sect.F, 69, 2013
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4IW1
 | | HSA-fructose complex | | 分子名称: | D-fructose, PHOSPHATE ION, Serum albumin, ... | | 著者 | Wang, Y, Yu, H, Shi, X, Huang, M. | | 登録日 | 2013-01-23 | | 公開日 | 2013-04-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Structural mechanism of ring-opening reaction of glucose by human serum albumin
J.Biol.Chem., 288, 2013
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4K2C
 | | HSA Ligand Free | | 分子名称: | Serum albumin | | 著者 | Wang, Y, Luo, Z, Shi, X, Huang, M. | | 登録日 | 2013-04-08 | | 公開日 | 2013-05-01 | | 最終更新日 | 2018-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.23 Å) | | 主引用文献 | Structural mechanism of ring-opening reaction of glucose by human serum albumin.
J. Biol. Chem., 288, 2013
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4K23
 | | Structure of anti-uPAR Fab ATN-658 | | 分子名称: | anti-uPAR antibody, heavy chain, light chain | | 著者 | Yuan, C, Huang, M, Chen, L. | | 登録日 | 2013-04-08 | | 公開日 | 2014-02-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Identification of a New Epitope in uPAR as a Target for the Cancer Therapeutic Monoclonal Antibody ATN-658, a Structural Homolog of the uPAR Binding Integrin CD11b ( alpha M)
Plos One, 9, 2014
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2I30
 | | Human serum albumin complexed with myristate and salicylic acid | | 分子名称: | 2-HYDROXYBENZOIC ACID, MYRISTIC ACID, Serum albumin | | 著者 | Yang, F, Bian, C, Zhu, L, Zhao, G, Huang, Z, Huang, M. | | 登録日 | 2006-08-17 | | 公開日 | 2006-12-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Effect of human serum albumin on drug metabolism: Structural evidence of esterase activity of human serum albumin
J.Struct.Biol., 157, 2007
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2I2Z
 | | Human serum albumin complexed with myristate and aspirin | | 分子名称: | 2-HYDROXYBENZOIC ACID, MYRISTIC ACID, Serum albumin | | 著者 | Yang, F, Bian, C, Zhu, L, Zhao, G, Huang, Z, Huang, M. | | 登録日 | 2006-08-17 | | 公開日 | 2006-12-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Effect of human serum albumin on drug metabolism: Structural evidence of esterase activity of human serum albumin
J.Struct.Biol., 157, 2007
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2NWN
 | | New Pharmacophore for Serine Protease Inhibition Revealed by Crystal Structure of Human Urokinase-type Plasminogen Activator Complexed with a Cyclic Peptidyl Inhibitor, upain-1 | | 分子名称: | Plasminogen activator, urokinase, upain-1 | | 著者 | Zhao, G, Yuan, C, Wind, T, Andreasen, P.A, Huang, Z, Huang, M, Structural Genomics Consortium (SGC) | | 登録日 | 2006-11-16 | | 公開日 | 2007-10-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural basis of specificity of a peptidyl urokinase inhibitor, upain-1
J.Struct.Biol., 160, 2007
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2O8U
 | | Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q/S195A) in complex with Inhibitors | | 分子名称: | BENZAMIDINE, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... | | 著者 | Zhao, G, Yuan, C, Jiang, L, Huang, Z, Huang, M. | | 登録日 | 2006-12-12 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q/S195A) in complex with Inhibitors
To be Published
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2O8T
 | | Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q) in complex with Inhibitors | | 分子名称: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, SULFATE ION, ... | | 著者 | Zhao, G, Yuan, C, Jiang, L, Huang, Z, Huang, M. | | 登録日 | 2006-12-12 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q/S195A) in complex with Inhibitors
To be Published
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2O8W
 | | Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q/S195A) in complex with Inhibitors | | 分子名称: | 1-phenylguanidine, SULFATE ION, TETRAETHYLENE GLYCOL, ... | | 著者 | Zhao, G, Yuan, C, Jiang, L, Huang, Z, Huang, M. | | 登録日 | 2006-12-12 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q/S195A) in complex with Inhibitors
To be Published
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5WXT
 | | Crystal structure of uPA-S195A in complex with S2444 | | 分子名称: | (2R)-N-[2-[[(2S)-1-[[4-[bis(oxidanyl)amino]phenyl]amino]-5-carbamimidamido-1-oxidanylidene-pentan-2-yl]amino]-2-oxidanylidene-ethyl]-5-oxidanylidene-pyrrolidine-2-carboxamide, Urokinase-type plasminogen activator chain B | | 著者 | Jiang, L, Huang, M. | | 登録日 | 2017-01-08 | | 公開日 | 2018-07-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of uPA-S195A in complex with S2444
To Be Published
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5WXP
 | | Crystal structure of uPA in complex with upain-2-3-W3A | | 分子名称: | ALANINE, CYSTEINE, Urokinase-type plasminogen activator chain B, ... | | 著者 | Jiang, L, Huang, M. | | 登録日 | 2017-01-08 | | 公開日 | 2018-07-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Cleavage of peptidic inhibitors by target protease is caused by peptide conformational transition.
Biochim. Biophys. Acta, 1862, 2018
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5WXQ
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5WXF
 | | Crystal structure of uPA in complex with upain-2-2 | | 分子名称: | SULFATE ION, Urokinase-type plasminogen activator chain B, upain-2-2 peptide | | 著者 | Jiang, L, Huang, M. | | 登録日 | 2017-01-07 | | 公開日 | 2018-07-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Cleavage of peptidic inhibitors by target protease is caused by peptide conformational transition.
Biochim. Biophys. Acta, 1862, 2018
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5WXR
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5WXO
 | | Crystal structure of uPA in complex with upain-2-2-W3A | | 分子名称: | Urokinase-type plasminogen activator chain B, upain-2-2-W3A peptide | | 著者 | Jiang, L, Huang, M. | | 登録日 | 2017-01-08 | | 公開日 | 2018-07-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Cleavage of peptidic inhibitors by target protease is caused by peptide conformational transition.
Biochim. Biophys. Acta, 1862, 2018
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5WXS
 | | Crystal structure of uPA in complex with S2444 | | 分子名称: | (2R)-N-[2-[[(2S)-5-carbamimidamido-1-oxidanylidene-pentan-2-yl]amino]-2-oxidanylidene-ethyl]-5-oxidanylidene-1,2-dihydropyrrole-2-carboxamide, Urokinase-type plasminogen activator chain B | | 著者 | Jiang, L, Huang, M. | | 登録日 | 2017-01-08 | | 公開日 | 2018-07-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of uPA in complex with S2444
To Be Published
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5Z9Y
 | | Crystal structure of Mycobacterium tuberculosis thiazole synthase (ThiG) complexed with DXP | | 分子名称: | 1-DEOXY-D-XYLULOSE-5-PHOSPHATE, Thiazole synthase | | 著者 | Zhang, J, Zhang, B, Zhao, Y, Yang, X, Huang, M, Cui, P, Zhang, W, Li, J, Zhang, Y. | | 登録日 | 2018-02-05 | | 公開日 | 2018-04-11 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Snapshots of catalysis: Structure of covalently bound substrate trapped in Mycobacterium tuberculosis thiazole synthase (ThiG).
Biochem. Biophys. Res. Commun., 497, 2018
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5ZLZ
 | | Structure of tPA and PAI-1 | | 分子名称: | GLYCEROL, Plasminogen activator inhibitor 1, Tissue-type plasminogen activator | | 著者 | Min, L, Huang, M. | | 登録日 | 2018-03-31 | | 公開日 | 2019-04-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.581 Å) | | 主引用文献 | Development of a PAI-1 trapping agent (PAItrap2) based on inactivated tPA-SPD and the crystal structure of PAItrap2 in complex with PAI-1
To Be Published
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7V63
 | | Structure of dimeric uPAR at low pH | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor | | 著者 | Yuan, C, Huang, M. | | 登録日 | 2021-08-19 | | 公開日 | 2021-12-22 | | 最終更新日 | 2022-04-06 | | 実験手法 | X-RAY DIFFRACTION (2.906 Å) | | 主引用文献 | Crystal structure and cellular functions of uPAR dimer
Nat Commun, 13, 2022
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7W7H
 | | S Suis FakA-FakB2 complex structure | | 分子名称: | OLEIC ACID, Predicted kinase related to dihydroxyacetone kinase, SULFATE ION, ... | | 著者 | Shi, Y, Zang, N, Lou, N, Xu, Y, Sun, J, Huang, M, Zhang, H, Lu, H, Zhou, C, Feng, Y. | | 登録日 | 2021-12-04 | | 公開日 | 2022-09-21 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure and mechanism for streptococcal fatty acid kinase (Fak) system dedicated to host fatty acid scavenging.
Sci Adv, 8, 2022
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7CJ1
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7E17
 | | Structure of dimeric uPAR | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor | | 著者 | Cai, Y, Huang, M. | | 登録日 | 2021-02-01 | | 公開日 | 2021-12-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | | 主引用文献 | Crystal structure and cellular functions of uPAR dimer
Nat Commun, 13, 2022
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