5ZLZ

Structure of tPA and PAI-1

Summary for 5ZLZ

• Entry DOI: 10.2210/pdb5zlz/pdb
• Descriptor: Plasminogen activator inhibitor 1, Tissue-type plasminogen activator, GLYCEROL (3 entities in total)
• Functional Keywords: pai-1, fibrinolysis, paitrap2, hydrolase inhibitor-hydrolase complex, hydrolase inhibitor/hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 70405.23

Authors

Min, L.,Huang, M. (deposition date: 2018-03-31, release date: 2019-04-03, Last modification date: 2024-10-30)

• Primary citation: Min, L.,Huang, M.; Development of a PAI-1 trapping agent (PAItrap2) based on inactivated tPA-SPD and the crystal structure of PAItrap2 in complex with PAI-1; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.581 Å)