5ZLZ

Structure of tPA and PAI-1

Summary for 5ZLZ

Entry DOI	10.2210/pdb5zlz/pdb
Descriptor	Plasminogen activator inhibitor 1, Tissue-type plasminogen activator, GLYCEROL (3 entities in total)
Functional Keywords	pai-1, fibrinolysis, paitrap2, hydrolase inhibitor-hydrolase complex, hydrolase inhibitor/hydrolase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	70405.23
Authors	Min, L.,Huang, M. (deposition date: 2018-03-31, release date: 2019-04-03, Last modification date: 2023-11-22)
Primary citation	Min, L.,Huang, M. Development of a PAI-1 trapping agent (PAItrap2) based on inactivated tPA-SPD and the crystal structure of PAItrap2 in complex with PAI-1 To Be Published,
Experimental method	X-RAY DIFFRACTION (3.581 Å)

Structure validation