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5FIT
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BU of 5fit by Molmil
FHIT-SUBSTRATE ANALOG
Descriptor: FRAGILE HISTIDINE TRIAD PROTEIN, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER
Authors:Lima, C.D, Klein, M.G, Hendrickson, W.A.
Deposit date:1997-09-25
Release date:1998-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-based analysis of catalysis and substrate definition in the HIT protein family.
Science, 278, 1997
3VA9
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BU of 3va9 by Molmil
Crystal structure of the Rhodopseudomonas palustris histidine kinase HK9 sensor domain
Descriptor: CHLORIDE ION, Sensor histidine kinase
Authors:Zhang, Z, Liu, Q, Hendrickson, W.A.
Deposit date:2011-12-29
Release date:2012-06-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the Rhodopseudomonas palustris histidine kinase HK9 sensor domain
To be Published
3V9F
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BU of 3v9f by Molmil
Crystal Structure of the extracellular domain of the putative hybrid two component system BT3049 from B. thetaiotaomicron
Descriptor: Two-component system sensor histidine kinase/response regulator, hybrid (One-component system)
Authors:Zhang, Z, Liu, Q, Hendrickson, W.A.
Deposit date:2011-12-27
Release date:2012-03-14
Last modified:2014-10-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structures of apparent saccharide sensors from histidine kinase receptors prevalent in a human gut symbiont.
Febs J., 281, 2014
3TX3
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BU of 3tx3 by Molmil
CysZ, a putative sulfate permease
Descriptor: CHLORIDE ION, LAURYL DIMETHYLAMINE-N-OXIDE, SULFATE ION, ...
Authors:Assur, Z, Liu, Q, Hendrickson, W.A, Mancia, F, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2011-09-22
Release date:2011-11-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:CysZ, a putative sulfate permease
To be Published
3VA6
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BU of 3va6 by Molmil
Crystal Structure of the extracellular domain of the putative hybrid two component system BT4673 from B. thetaiotaomicron
Descriptor: Two-component system sensor histidine kinase
Authors:Zhang, Z, Liu, Q, Hendrickson, W.A.
Deposit date:2011-12-28
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Extraellular Domain Structures of Two Potential Saccharide-sensing Two-component Systems from a Human Gut Symbiont
To be Published
5WUC
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BU of 5wuc by Molmil
Structural basis for conductance through TRIC cation channels
Descriptor: SODIUM ION, Uncharacterized protein
Authors:Su, M, Gao, F, Mao, Y, Li, D.L, Guo, Y.Z, Wang, X.H, Bruni, R, Kloss, B, Hendrickson, W.A, Chen, Y.H, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2016-12-17
Release date:2017-07-12
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for conductance through TRIC cation channels.
Nat Commun, 8, 2017
5WUD
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BU of 5wud by Molmil
Structural basis for conductance through TRIC cation channels
Descriptor: MAGNESIUM ION, Uncharacterized protein
Authors:Su, M, Gao, F, Mao, Y, Li, D.L, Guo, Y.Z, Wang, X.H, Bruni, R, Kloss, B, Hendrickson, W.A, Chen, Y.H, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2016-12-17
Release date:2017-06-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for conductance through TRIC cation channels.
Nat Commun, 8, 2017
5WUE
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BU of 5wue by Molmil
Structural basis for conductance through TRIC cation channels
Descriptor: SULFATE ION, Uncharacterized protein
Authors:Su, M, Gao, F, Mao, Y, Li, D.L, Guo, Y.Z, Wang, X.H, Bruni, R, Kloss, B, Hendrickson, W.A, Chen, Y.H, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2016-12-17
Release date:2017-06-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for conductance through TRIC cation channels.
Nat Commun, 8, 2017
5WUF
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BU of 5wuf by Molmil
Structural basis for conductance through TRIC cation channels
Descriptor: CADMIUM ION, Putative membrane protein
Authors:Mao, Y, Gao, F, Su, M, Wang, X.H, Zeng, Y, Bruni, R, Kloss, B, Hendrickson, W.A, Chen, Y.H, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2016-12-17
Release date:2017-08-09
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Structural basis for conductance through TRIC cation channels.
Nat Commun, 8, 2017
6C5Y
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BU of 6c5y by Molmil
Crystal structure of thaumatin from microcrystals
Descriptor: Thaumatin-1
Authors:Guo, G, Fuchs, M, Shi, W, Skinner, J, Berman, E, Ogata, C.M, Hendrickson, W.A, McSweeney, S, Liu, Q.
Deposit date:2018-01-17
Release date:2018-05-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Sample manipulation and data assembly for robust microcrystal synchrotron crystallography.
IUCrJ, 5, 2018
4JN4
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BU of 4jn4 by Molmil
Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK, GLYCEROL, ...
Authors:Qi, R, Sarbeng, E.B, Liu, Q, Le, K.Q, Xu, X, Xu, H, Yang, J, Wong, J.L, Vorvis, C, Hendrickson, W.A, Zhou, L, Liu, Q.
Deposit date:2013-03-14
Release date:2013-05-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP.
Nat.Struct.Mol.Biol., 20, 2013
4JNE
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BU of 4jne by Molmil
Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Hsp70 CHAPERONE DnaK, ...
Authors:Qi, R, Sarbeng, E.B, Liu, Q, Le, K.Q, Xu, X, Xu, H, Yang, J, Wong, J.L, Vorvis, C, Hendrickson, W.A, Zhou, L, Liu, Q.
Deposit date:2013-03-15
Release date:2013-05-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP.
Nat.Struct.Mol.Biol., 20, 2013
4JNF
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BU of 4jnf by Molmil
Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP
Descriptor: Hsp70 CHAPERONE DnaK
Authors:Qi, R, Sarbeng, E.B, Liu, Q, Le, K.Q, Xu, X, Xu, H, Yang, J, Wong, J.L, Vorvis, C, Hendrickson, W.A, Zhou, L, Liu, Q.
Deposit date:2013-03-15
Release date:2013-05-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.621 Å)
Cite:Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP.
Nat.Struct.Mol.Biol., 20, 2013
7N46
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BU of 7n46 by Molmil
ADP-binding state of the nucleotide-binding domain of Hsp70 DnaK
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein DnaK, MAGNESIUM ION, ...
Authors:Wang, W, Hendrickson, W.A.
Deposit date:2021-06-03
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Visualization of Hsp70-catalyzed ATP Hydrolysis
To Be Published
7NP4
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BU of 7np4 by Molmil
cAMP-bound rabbit HCN4 stabilized in LMNG-CHS detergent mixture
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Authors:Giese, H, Chaves-Sanjuan, A, Saponaro, A, Clarke, O, Bolognesi, M, Mancia, F, Hendrickson, W.A, Thiel, G, Santoro, B, Moroni, A.
Deposit date:2021-02-26
Release date:2021-08-11
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Gating movements and ion permeation in HCN4 pacemaker channels.
Mol.Cell, 81, 2021
7NP3
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BU of 7np3 by Molmil
cAMP-free rabbit HCN4 stabilized in LMNG-CHS detergent mixture
Descriptor: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Authors:Giese, H.M, Chaves-Sanjuan, A, Saponaro, A, Clarke, O, Bolognesi, M, Mancia, F, Hendrickson, W.A, Thiel, G, Santoro, B, Moroni, A.
Deposit date:2021-02-26
Release date:2021-08-11
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Gating movements and ion permeation in HCN4 pacemaker channels.
Mol.Cell, 81, 2021
4I54
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BU of 4i54 by Molmil
Crystal structure of clade A/E 93TH057 HIV-1 gp120 H375S core in complex with DMJ-II-121
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 glycoprotein, ...
Authors:Le-Khac, M, Hendrickson, W.A.
Deposit date:2012-11-28
Release date:2013-05-29
Last modified:2021-05-26
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-Based Design and Synthesis of an HIV-1 Entry Inhibitor Exploiting X-Ray and Thermodynamic Characterization.
ACS Med Chem Lett, 4, 2013
4I53
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BU of 4i53 by Molmil
Crystal structure of clade C1086 HIV-1 gp120 core in complex with DMJ-II-121
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FORMIC ACID, HIV-1 glycoprotein, ...
Authors:Le-Khac, M, Hendrickson, W.A.
Deposit date:2012-11-28
Release date:2013-05-29
Last modified:2021-05-26
Method:X-RAY DIFFRACTION (2.5002 Å)
Cite:Structure-Based Design and Synthesis of an HIV-1 Entry Inhibitor Exploiting X-Ray and Thermodynamic Characterization.
ACS Med Chem Lett, 4, 2013
1MSB
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BU of 1msb by Molmil
STRUCTURE OF THE CALCIUM-DEPENDENT LECTIN DOMAIN FROM A RAT MANNOSE-BINDING PROTEIN DETERMINED BY MAD PHASING
Descriptor: HOLMIUM ATOM, MANNOSE-BINDING PROTEIN-A
Authors:Weis, W.I, Drickamer, K, Hendrickson, W.A.
Deposit date:1991-09-23
Release date:1992-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the calcium-dependent lectin domain from a rat mannose-binding protein determined by MAD phasing.
Science, 254, 1991
6D9Z
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BU of 6d9z by Molmil
Structure of CysZ, a sulfate permease from Pseudomonas Denitrificans
Descriptor: Sulfate transporter CysZ, octyl beta-D-glucopyranoside
Authors:Sanghai, Z.A, Clarke, O.B, Liu, Q, Banerjee, S, Rajashankar, K.R, Hendrickson, W.A, Mancia, F.
Deposit date:2018-04-30
Release date:2018-05-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.4021318 Å)
Cite:Structure-based analysis of CysZ-mediated cellular uptake of sulfate.
Elife, 7, 2018
6D79
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BU of 6d79 by Molmil
Structure of CysZ, a sulfate permease from Pseudomonas Fragi
Descriptor: Sulfate transporter CysZ
Authors:Sanghai, Z.A, Liu, Q, Clarke, O.B, Banerjee, S, Rajashankar, K.R, Hendrickson, W.A, Mancia, F.
Deposit date:2018-04-24
Release date:2018-05-16
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (3.501 Å)
Cite:Structure-based analysis of CysZ-mediated cellular uptake of sulfate.
Elife, 7, 2018
2FIT
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BU of 2fit by Molmil
FHIT (FRAGILE HISTIDINE TRIAD PROTEIN)
Descriptor: FRAGILE HISTIDINE PROTEIN, SULFATE ION, beta-D-fructofuranose
Authors:Lima, C.D, D'Amico, K.L, Naday, I, Rosenbaum, G, Westbrook, E.M, Hendrickson, W.A.
Deposit date:1997-05-17
Release date:1997-11-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:MAD analysis of FHIT, a putative human tumor suppressor from the HIT protein family.
Structure, 5, 1997
2HB5
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BU of 2hb5 by Molmil
Crystal Structure of the Moloney Murine Leukemia Virus RNase H Domain
Descriptor: MAGNESIUM ION, Reverse transcriptase/ribonuclease H, SULFATE ION
Authors:Lim, D, Gregorio, G.G, Bingman, C.A, Martinez-Hackert, E, Hendrickson, W.A, Goff, S.P.
Deposit date:2006-06-13
Release date:2006-08-29
Last modified:2023-03-22
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Crystal Structure of the Moloney Murine Leukemia Virus RNase H Domain.
J.Virol., 80, 2006
8D1G
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BU of 8d1g by Molmil
hBest2 Ca2+-bound open state
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, Bestrophin-2, ...
Authors:Owji, A.P, Kittredge, A, Hendrickson, W.A, Tingting, Y.
Deposit date:2022-05-27
Release date:2022-07-13
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.07 Å)
Cite:Structures and gating mechanisms of human bestrophin anion channels.
Nat Commun, 13, 2022
8D1O
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BU of 8d1o by Molmil
hBest1_345 Ca2+-bound open state
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Bestrophin-1, CALCIUM ION
Authors:Owji, A.P, Kittredge, A, Hendrickson, W.A, Tingting, Y.
Deposit date:2022-05-27
Release date:2022-07-13
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.44 Å)
Cite:Structures and gating mechanisms of human bestrophin anion channels.
Nat Commun, 13, 2022

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