3TWQ
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![BU of 3twq by Molmil](/molmil-images/mine/3twq) | |
3TWW
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3TWS
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![BU of 3tws by Molmil](/molmil-images/mine/3tws) | Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human TERF1 (chimeric peptide) | Descriptor: | 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, HEXAETHYLENE GLYCOL, ... | Authors: | Guettler, S, Sicheri, F. | Deposit date: | 2011-09-22 | Release date: | 2011-12-07 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease. Cell(Cambridge,Mass.), 147, 2011
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3TWX
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![BU of 3twx by Molmil](/molmil-images/mine/3twx) | Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human FNBP1 (chimeric peptide) | Descriptor: | 1,2-ETHANEDIOL, HEXAETHYLENE GLYCOL, SULFATE ION, ... | Authors: | Guettler, S, Sicheri, F. | Deposit date: | 2011-09-22 | Release date: | 2011-12-07 | Last modified: | 2011-12-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease. Cell(Cambridge,Mass.), 147, 2011
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3TWT
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![BU of 3twt by Molmil](/molmil-images/mine/3twt) | Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human MCL1 (chimeric peptide) | Descriptor: | 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, NONAETHYLENE GLYCOL, ... | Authors: | Guettler, S, Sicheri, F. | Deposit date: | 2011-09-22 | Release date: | 2011-12-07 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease. Cell(Cambridge,Mass.), 147, 2011
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3TWR
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![BU of 3twr by Molmil](/molmil-images/mine/3twr) | Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human 3BP2 | Descriptor: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, SH3 domain-binding protein 2, SULFATE ION, ... | Authors: | Guettler, S, Sicheri, F. | Deposit date: | 2011-09-22 | Release date: | 2011-12-07 | Last modified: | 2011-12-28 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease. Cell(Cambridge,Mass.), 147, 2011
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3TWV
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![BU of 3twv by Molmil](/molmil-images/mine/3twv) | Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human NUMA1 (chimeric peptide) | Descriptor: | 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, SULFATE ION, ... | Authors: | Guettler, S, Sicheri, F. | Deposit date: | 2011-09-22 | Release date: | 2011-12-07 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease. Cell(Cambridge,Mass.), 147, 2011
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3TWU
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![BU of 3twu by Molmil](/molmil-images/mine/3twu) | |
5JRT
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![BU of 5jrt by Molmil](/molmil-images/mine/5jrt) | |
8ALY
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![BU of 8aly by Molmil](/molmil-images/mine/8aly) | Cryo-EM structure of human tankyrase 2 SAM-PARP filament (G1032W mutant) | Descriptor: | Poly [ADP-ribose] polymerase tankyrase-2, ZINC ION | Authors: | Mariotti, L, Inian, O, Desfosses, A, Beuron, F, Morris, E.P, Guettler, S. | Deposit date: | 2022-08-01 | Release date: | 2022-11-16 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Structural basis of tankyrase activation by polymerization. Nature, 612, 2022
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2V51
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![BU of 2v51 by Molmil](/molmil-images/mine/2v51) | Structure of MAL-RPEL1 complexed to actin | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Mouilleron, S, Guettler, S, Langer, C.A, Treisman, R, McDonald, N.Q. | Deposit date: | 2008-10-01 | Release date: | 2008-11-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL. EMBO J., 27, 2008
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2V52
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![BU of 2v52 by Molmil](/molmil-images/mine/2v52) | Structure of MAL-RPEL2 complexed to G-actin | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Mouilleron, S, Guettler, S, Langer, C.A, Treisman, R, McDonald, N.Q. | Deposit date: | 2008-10-01 | Release date: | 2008-11-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL. EMBO J., 27, 2008
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2YJE
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![BU of 2yje by Molmil](/molmil-images/mine/2yje) | Oligomeric assembly of actin bound to MRTF-A | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Mouilleron, S, Langer, C.A, Guettler, S, McDonald, N.Q, Treisman, R. | Deposit date: | 2011-05-19 | Release date: | 2011-07-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of a pentavalent G-actin*MRTF-A complex reveals how G-actin controls nucleocytoplasmic shuttling of a transcriptional coactivator. Sci Signal, 4, 2011
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2YJF
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![BU of 2yjf by Molmil](/molmil-images/mine/2yjf) | Oligomeric assembly of actin bound to MRTF-A | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Mouilleron, S, Langer, C.A, Guettler, S, McDonald, N.Q, Treisman, R. | Deposit date: | 2011-05-19 | Release date: | 2011-07-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure of a pentavalent G-actin*MRTF-A complex reveals how G-actin controls nucleocytoplasmic shuttling of a transcriptional coactivator. Sci Signal, 4, 2011
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6BXI
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![BU of 6bxi by Molmil](/molmil-images/mine/6bxi) | X-ray crystal structure of NDR1 kinase domain | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase 38 | Authors: | Xiong, S, Sicheri, F. | Deposit date: | 2017-12-18 | Release date: | 2018-08-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment. Structure, 26, 2018
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5TWG
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![BU of 5twg by Molmil](/molmil-images/mine/5twg) | |
5TWH
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![BU of 5twh by Molmil](/molmil-images/mine/5twh) | |
5TWF
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![BU of 5twf by Molmil](/molmil-images/mine/5twf) | |
5JU5
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![BU of 5ju5 by Molmil](/molmil-images/mine/5ju5) | |
5JTI
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![BU of 5jti by Molmil](/molmil-images/mine/5jti) | |
1OPK
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![BU of 1opk by Molmil](/molmil-images/mine/1opk) | Structural basis for the auto-inhibition of c-Abl tyrosine kinase | Descriptor: | 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, GLYCEROL, MYRISTIC ACID, ... | Authors: | Nagar, B, Hantschel, O, Young, M.A, Scheffzek, K, Veach, D, Bornmann, W, Clarkson, B, Superti-Furga, G, Kuriyan, J. | Deposit date: | 2003-03-06 | Release date: | 2003-04-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for the autoinhibition of c-Abl tyrosine kinase Cell(Cambridge,Mass.), 112, 2003
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1OPJ
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![BU of 1opj by Molmil](/molmil-images/mine/1opj) | Structural basis for the auto-inhibition of c-Abl tyrosine kinase | Descriptor: | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, CHLORIDE ION, MYRISTIC ACID, ... | Authors: | Nagar, B, Hantschel, O, Young, M.A, Scheffzek, K, Veach, D, Bornmann, W, Clarkson, B, Superti-Furga, G, Kuriyan, J. | Deposit date: | 2003-03-06 | Release date: | 2003-04-08 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural basis for the autoinhibition of c-Abl tyrosine kinase Cell(Cambridge,Mass.), 112, 2003
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1OPL
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![BU of 1opl by Molmil](/molmil-images/mine/1opl) | Structural basis for the auto-inhibition of c-Abl tyrosine kinase | Descriptor: | 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, MYRISTIC ACID, proto-oncogene tyrosine-protein kinase | Authors: | Nagar, B, Hantschel, O, Young, M.A, Scheffzek, K, Veach, D, Bornmann, W, Clarkson, B, Superti-Furga, G, Kuriyan, J. | Deposit date: | 2003-03-06 | Release date: | 2003-04-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.42 Å) | Cite: | Structural basis for the autoinhibition of c-Abl tyrosine kinase Cell(Cambridge,Mass.), 112, 2003
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