6BXI

X-ray crystal structure of NDR1 kinase domain

Summary for 6BXI

Entry DOI	10.2210/pdb6bxi/pdb
Descriptor	Serine/threonine-protein kinase 38, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	kinase fold with atypically long activation segment, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	78567.93
Authors	Xiong, S.,Sicheri, F. (deposition date: 2017-12-18, release date: 2018-08-29, Last modification date: 2024-03-13)
Primary citation	Xiong, S.,Lorenzen, K.,Couzens, A.L.,Templeton, C.M.,Rajendran, D.,Mao, D.Y.L.,Juang, Y.C.,Chiovitti, D.,Kurinov, I.,Guettler, S.,Gingras, A.C.,Sicheri, F. Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment. Structure, 26:1101-1115.e6, 2018 Cited by PubMed: 29983373 DOI: 10.1016/j.str.2018.05.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation