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8FWT
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Structure of the amino terminal domain of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 and competitive antagonist DNQX
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者Yen, L.Y, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2023-01-23
公開日2023-04-19
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Positive and negative allosteric modulation of GluK2 kainate receptors by BPAM344 and antiepileptic perampanel.
Cell Rep, 42, 2023
8SS4
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Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 (apo state)
分子名称: Glutamate receptor 2, Voltage-dependent calcium channel gamma-5 subunit chimera, Protein cornichon homolog 2, ...
著者Yen, L.Y, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2023-05-08
公開日2023-09-06
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
8SS5
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Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunit TARP gamma-5 (apo state)
分子名称: Glutamate receptor 2, Voltage-dependent calcium channel gamma-5 subunit chimera, SODIUM ION
著者Yen, L.Y, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2023-05-08
公開日2023-09-06
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (3.56 Å)
主引用文献Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
7RZA
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BU of 7rza by Molmil
Structure of the complex of AMPA receptor GluA2 with auxiliary subunit GSG1L bound to agonist quisqualate
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2
著者Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2021-08-27
公開日2021-10-27
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (4.26 Å)
主引用文献Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
7RZ5
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Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK 200775
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Glutamate receptor 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
著者Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2021-08-27
公開日2021-10-27
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
7RYZ
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BU of 7ryz by Molmil
Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit GSG1L bound to agonist quisqualate
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2
著者Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2021-08-26
公開日2021-10-27
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (4.15 Å)
主引用文献Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
7RZ9
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Structure of the complex of AMPA receptor GluA2 with auxiliary subunit GSG1L in the apo state
分子名称: Glutamate receptor 2
著者Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2021-08-27
公開日2021-10-27
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (4.15 Å)
主引用文献Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
7RZ4
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BU of 7rz4 by Molmil
Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK 200775
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2, ...
著者Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2021-08-27
公開日2021-10-27
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
9B33
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BU of 9b33 by Molmil
Structure of concanavalin A (ConA) dimer from the open-state structure of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to one ConA dimer. Type II interface between GluK2 ligand-binding domain and ConA
分子名称: CALCIUM ION, Concanavalin V, ZINC ION
著者Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I.
登録日2024-03-18
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (4.07 Å)
主引用文献Kainate receptor channel opening and gating mechanism
Nature, 2024
9B34
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BU of 9b34 by Molmil
Structure of concanavalin A (ConA) dimer from the open-state structure of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to two ConA dimers. Type I interface between GluK2 ligand-binding domain and ConA
分子名称: CALCIUM ION, Concanavalin A, ZINC ION
著者Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I.
登録日2024-03-18
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Kainate receptor channel opening and gating mechanism
Nature, 2024
9B35
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BU of 9b35 by Molmil
Ligand-binding and transmembrane domains of kainate receptor GluK2 in the open state, a complex with agonist glutamate and positive allosteric modulator BPAM344
分子名称: GLUTAMIC ACID, Glutamate receptor ionotropic, kainate 2
著者Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I.
登録日2024-03-18
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Kainate receptor channel opening and gating mechanism
Nature, 2024
9B36
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BU of 9b36 by Molmil
Open state of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to two concanavalin A dimers. Composite map.
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I.
登録日2024-03-18
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (4.29 Å)
主引用文献Kainate receptor channel opening and gating mechanism
Nature, 2024
9B37
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BU of 9b37 by Molmil
Open state of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to one concanavalin A dimer. Composite map.
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I.
登録日2024-03-18
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (6.66 Å)
主引用文献Kainate receptor channel opening and gating mechanism
Nature, 2024
9B38
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BU of 9b38 by Molmil
Kainate receptor GluK2 in complex with agonist glutamate with pseudo 4-fold symmetrical ligand-binding domain layer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I.
登録日2024-03-18
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Kainate receptor channel opening and gating mechanism
Nature, 2024
9B39
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BU of 9b39 by Molmil
Kainate receptor GluK2 in complex with agonist glutamate with asymmetric ligand-binding domain layer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I.
登録日2024-03-18
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Kainate receptor channel opening and gating mechanism
Nature, 2024
5YBC
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BU of 5ybc by Molmil
X-ray structure of native ETS-domain domain of Ergp55
分子名称: GLYCEROL, Transcriptional regulator ERG
著者Saxena, A.K, Gangwar, S.P.
登録日2017-09-04
公開日2018-09-19
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Comparative structure analysis of the ETSi domain of ERG3 and its complex with the E74 promoter DNA sequence
Acta Crystallogr F Struct Biol Commun, 74, 2018
5YBD
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BU of 5ybd by Molmil
X-ray structure of ETS domain of Ergp55 in complex with E74DNA
分子名称: DNA (5'-D(P*AP*CP*CP*GP*GP*AP*AP*GP*T)-3'), DNA (5'-D(P*CP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), Transcriptional regulator ERG
著者Saxena, A.K, Gangwar, S.P.
登録日2017-09-04
公開日2018-11-14
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.769 Å)
主引用文献Comparative structure analysis of the ETSi domain of ERG3 and its complex with the E74 promoter DNA sequence
Acta Crystallogr F Struct Biol Commun, 74, 2018
7RZ7
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BU of 7rz7 by Molmil
Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist Quisqualate
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2
著者Klykov, O.V, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2021-08-27
公開日2021-10-27
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
7RZ6
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BU of 7rz6 by Molmil
Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist glutamate
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GLUTAMIC ACID, Glutamate receptor 2
著者Klykov, O.V, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2021-08-27
公開日2021-10-27
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
7RYY
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BU of 7ryy by Molmil
Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist glutamate
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GLUTAMIC ACID, Glutamate receptor 2
著者Klykov, O.V, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2021-08-26
公開日2021-10-27
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
7RZ8
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BU of 7rz8 by Molmil
Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist quisqualate
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Glutamate receptor 2
著者Klykov, O.V, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2021-08-27
公開日2021-10-27
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
8BHF
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BU of 8bhf by Molmil
Cryo-EM structure of stalled rabbit 80S ribosomes in complex with human CCR4-NOT and CNOT4
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S11, ...
著者Absmeier, E, Chandrasekaran, V, O'Reilly, F.J, Stowell, J.A.W, Rappsilber, J, Passmore, L.A.
登録日2022-10-31
公開日2023-09-06
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
7KBU
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BU of 7kbu by Molmil
Structure of Hevin FS-EC
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Machius, M, Fan, S, Rudenko, G.
登録日2020-10-03
公開日2021-02-10
最終更新日2021-07-14
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Interplay between hevin, SPARC, and MDGAs: Modulators of neurexin-neuroligin transsynaptic bridges.
Structure, 29, 2021
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