8SS5
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunit TARP gamma-5 (apo state)
Summary for 8SS5
Entry DOI | 10.2210/pdb8ss5/pdb |
EMDB information | 40741 40742 40743 40744 40745 40746 40747 40748 40749 40750 |
Descriptor | Glutamate receptor 2, Voltage-dependent calcium channel gamma-5 subunit chimera, SODIUM ION (2 entities in total) |
Functional Keywords | ampa receptor, neurotransmission, tarp gamma-5, ion-channel, signaling protein |
Biological source | Rattus norvegicus (Norway rat) More |
Total number of polymer chains | 4 |
Total formula weight | 459938.43 |
Authors | Yen, L.Y.,Gangwar, S.P.,Yelshanskaya, M.V.,Sobolevsky, A.I. (deposition date: 2023-05-08, release date: 2023-09-06, Last modification date: 2023-10-25) |
Primary citation | Gangwar, S.P.,Yen, L.Y.,Yelshanskaya, M.V.,Korman, A.,Jones, D.R.,Sobolevsky, A.I. Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2. Nat.Struct.Mol.Biol., 30:1481-1494, 2023 Cited by PubMed: 37653241DOI: 10.1038/s41594-023-01080-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.56 Å) |
Structure validation
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