8BHF

Cryo-EM structure of stalled rabbit 80S ribosomes in complex with human CCR4-NOT and CNOT4

This is a non-PDB format compatible entry.

Summary for 8BHF

• Entry DOI: 10.2210/pdb8bhf/pdb
• EMDB information: 16052
• Descriptor: Ribosomal protein L15, TRASH domain-containing protein, Ribosomal protein L23/L25 N-terminal domain-containing protein, ... (88 entities in total)
• Functional Keywords: translational control, mrna decay, deadenylation, ribosome stalling, human ccr4-not, ribosome
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 86
• Total formula weight: 3706651.19

Authors

Absmeier, E.,Chandrasekaran, V.,O'Reilly, F.J.,Stowell, J.A.W.,Rappsilber, J.,Passmore, L.A. (deposition date: 2022-10-31, release date: 2023-09-06, Last modification date: 2023-11-01)

• Primary citation: Gangwar, S.P.,Yen, L.Y.,Yelshanskaya, M.V.,Korman, A.,Jones, D.R.,Sobolevsky, A.I.; Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.; Nat.Struct.Mol.Biol., 30:1481-1494, 2023; PubMed: 37653241; DOI: 10.1038/s41594-023-01080-x

Experimental method

ELECTRON MICROSCOPY (3.1 Å)