7RZ8

Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist quisqualate

Summary for 7RZ8

Entry DOI	10.2210/pdb7rz8/pdb
EMDB information	24754
Descriptor	Glutamate receptor 2, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID (3 entities in total)
Functional Keywords	ampa receptor, ion channel, neurotransmission, synapse, tarp gamma-5, membrane protein
Biological source	Rattus norvegicus (Rat)
Total number of polymer chains	4
Total formula weight	482145.17
Authors	Klykov, O.V.,Gangwar, S.P.,Yelshanskaya, M.V.,Sobolevsky, A.I. (deposition date: 2021-08-27, release date: 2021-10-27, Last modification date: 2022-02-16)
Primary citation	Klykov, O.,Gangwar, S.P.,Yelshanskaya, M.V.,Yen, L.,Sobolevsky, A.I. Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81:4771-4783.e7, 2021 Cited by PubMed: 34678168 DOI: 10.1016/j.molcel.2021.09.030 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.1 Å)

Structure validation