3DO4
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3DJR
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3DJT
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3DK0
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3CXF
| Crystal structure of transthyretin variant Y114H | Descriptor: | Transthyretin | Authors: | Cendron, L, Zanotti, G, Folli, C, Alfieri, B, Pasquato, N, Berni, R. | Deposit date: | 2008-04-24 | Release date: | 2009-04-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and mutational analyses of protein-protein interactions between transthyretin and retinol-binding protein. Febs J., 275, 2008
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3DK2
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5AKT
| Transthyretin binding heterogeneity and anti-amyloidogenic activity of natural polyphenols and their metabolites: resveratrol-4'-O- glucuronide | Descriptor: | Resveratrol-4'-O-glucuronide, SULFATE ION, TRANSTHYRETIN | Authors: | Florio, P, Folli, C, Cianci, M, Del Rio, D, Zanotti, G, Berni, R. | Deposit date: | 2015-03-05 | Release date: | 2015-10-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Transthyretin Binding Heterogeneity and Anti-Amyloidogenic Activity of Natural Polyphenols and Their Metabolites J.Biol.Chem., 290, 2015
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2O73
| Structure of OHCU decarboxylase in complex with allantoin | Descriptor: | 1-(2,5-DIOXO-2,5-DIHYDRO-1H-IMIDAZOL-4-YL)UREA, OHCU decarboxylase | Authors: | Cendron, L, Berni, R, Folli, C, Ramazzina, I, Percudani, R, Zanotti, G. | Deposit date: | 2006-12-10 | Release date: | 2007-04-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation. J.Biol.Chem., 282, 2007
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2O70
| Structure of OHCU decarboxylase from zebrafish | Descriptor: | OHCU decarboxylase | Authors: | Cendron, L, Berni, R, Folli, C, Ramazzina, I, Percudani, R, Zanotti, G. | Deposit date: | 2006-12-09 | Release date: | 2007-04-10 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation. J.Biol.Chem., 282, 2007
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2O74
| Structure of OHCU decarboxylase in complex with guanine | Descriptor: | GUANINE, OHCU decarboxylase | Authors: | Cendron, L, Berni, R, Folli, C, Ramazzina, I, Percudani, R, Zanotti, G. | Deposit date: | 2006-12-10 | Release date: | 2007-04-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation. J.Biol.Chem., 282, 2007
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2NOY
| Crystal structure of transthyretin mutant I84S at PH 7.5 | Descriptor: | Transthyretin | Authors: | Pasquato, N, Berni, R, Folli, C, Alfieri, B, Cendron, L, Zanotti, G. | Deposit date: | 2006-10-26 | Release date: | 2007-01-16 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Acidic pH-induced conformational changes in amyloidogenic mutant transthyretin J.Mol.Biol., 366, 2007
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2G3Z
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2G4G
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2G4E
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2G3X
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3CL6
| Crystal structure of Puue Allantoinase | Descriptor: | Puue allantoinase | Authors: | Ramazzina, I, Cendron, L, Folli, C, Berni, R, Monteverdi, D, Zanotti, G, Percudani, R. | Deposit date: | 2008-03-18 | Release date: | 2008-06-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Logical identification of an allantoinase analog (puuE) recruited from polysaccharide deacetylases J.Biol.Chem., 283, 2008
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3CL7
| Crystal structure of Puue Allantoinase in complex with Hydantoin | Descriptor: | Puue Allantoinase, imidazolidine-2,4-dione | Authors: | Ramazzina, I, Cendron, L, Folli, C, Berni, R, Monteverdi, D, Zanotti, G, Percudani, R. | Deposit date: | 2008-03-18 | Release date: | 2008-06-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Logical identification of an allantoinase analog (puuE) recruited from polysaccharide deacetylases J.Biol.Chem., 283, 2008
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3CL8
| Crystal structure of Puue Allantoinase complexed with ACA | Descriptor: | 5-amino-1H-imidazole-4-carboxamide, Puue Allantoinase | Authors: | Ramazzina, I, Cendron, L, Folli, C, Berni, R, Monteverdi, D, Zanotti, G, Percudani, R. | Deposit date: | 2008-03-18 | Release date: | 2008-06-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Logical identification of an allantoinase analog (puuE) recruited from polysaccharide deacetylases J.Biol.Chem., 283, 2008
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5M98
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5Z5M
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8C86
| Crystal structure of human transthyretin in complex with 3-O-methyltolcapone analogue 2 | Descriptor: | (2,4-dimethylphenyl)-(3-methoxy-5-nitro-4-oxidanyl-phenyl)methanone, Transthyretin | Authors: | Poonsiri, T, Benini, S, Loconte, V, Cianci, M. | Deposit date: | 2023-01-18 | Release date: | 2024-01-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | 3-O-Methyltolcapone and Its Lipophilic Analogues Are Potent Inhibitors of Transthyretin Amyloidogenesis with High Permeability and Low Toxicity. Int J Mol Sci, 25, 2023
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8C85
| Crystal structure of human transthyretin in complex with 3-O-methyltolcapone analogue 1 | Descriptor: | (3,5-dimethylphenyl)-(3-methoxy-5-nitro-4-oxidanyl-phenyl)methanone, Transthyretin | Authors: | Poonsiri, T, Benini, S, Loconte, V, Cianci, M. | Deposit date: | 2023-01-18 | Release date: | 2024-01-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.19 Å) | Cite: | 3-O-Methyltolcapone and Its Lipophilic Analogues Are Potent Inhibitors of Transthyretin Amyloidogenesis with High Permeability and Low Toxicity. Int J Mol Sci, 25, 2023
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1QQF
| N-TERMINALLY TRUNCATED C3D,G FRAGMENT OF THE COMPLEMENT SYSTEM | Descriptor: | PROTEIN (COMPLEMENT C3DG) | Authors: | Zanotti, G, Bassetto, A, Battistutta, R, Stoppini, M, Berni, R. | Deposit date: | 1999-06-04 | Release date: | 2000-07-31 | Last modified: | 2015-01-21 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure at 1.44 A resolution of an N-terminally truncated form of the rat serum complement C3d fragment. Biochim.Biophys.Acta, 1478, 2000
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3Q1E
| Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase in complex with T4 | Descriptor: | 3,5,3',5'-TETRAIODO-L-THYRONINE, 5-hydroxyisourate hydrolase | Authors: | Cendron, L, Ramazzina, I, Percudani, R, Zanotti, G, Berni, R. | Deposit date: | 2010-12-17 | Release date: | 2011-05-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign. J.Mol.Biol., 409, 2011
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5AKS
| Transthyretin binding heterogeneity and anti-amyloidogenic activity of natural polyphenols and their metabolites: resveratrol-3-O- glucuronide | Descriptor: | DIMETHYL SULFOXIDE, Resveratrol-3-O-glucuronide, SULFATE ION, ... | Authors: | Florio, P, Foll, C, Cianci, M, Del Rio, D, Zanotti, G, Berni, R. | Deposit date: | 2015-03-05 | Release date: | 2015-10-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Transthyretin Binding Heterogeneity and Anti-Amyloidogenic Activity of Natural Polyphenols and Their Metabolites J.Biol.Chem., 290, 2015
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