2NOY

Crystal structure of transthyretin mutant I84S at PH 7.5

Summary for 2NOY

Entry DOI	10.2210/pdb2noy/pdb
Related	2G3X 2G3Z 2G4E 2G4G
Descriptor	Transthyretin (2 entities in total)
Functional Keywords	ttr, amyloid fibrils, point mutation, transport protein
Biological source	Homo sapiens (human)
Cellular location	Secreted: P02766
Total number of polymer chains	2
Total formula weight	27502.56
Authors	Pasquato, N.,Berni, R.,Folli, C.,Alfieri, B.,Cendron, L.,Zanotti, G. (deposition date: 2006-10-26, release date: 2007-01-16, Last modification date: 2023-10-25)
Primary citation	Pasquato, N.,Berni, R.,Folli, C.,Alfieri, B.,Cendron, L.,Zanotti, G. Acidic pH-induced conformational changes in amyloidogenic mutant transthyretin J.Mol.Biol., 366:711-719, 2007 Cited by PubMed: 17196219 DOI: 10.1016/j.jmb.2006.11.076 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation