1LDJ
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![BU of 1ldj by Molmil](/molmil-images/mine/1ldj) | Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex | Descriptor: | Cullin homolog 1, ZINC ION, ring-box protein 1 | Authors: | Zheng, N, Schulman, B.A, Song, L, Miller, J.J, Jeffrey, P.D, Wang, P, Chu, C, Koepp, D.M, Elledge, S.J, Pagano, M, Conaway, R.C, Conaway, J.W, Harper, J.W, Pavletich, N.P. | Deposit date: | 2002-04-08 | Release date: | 2002-05-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature, 416, 2002
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1LDD
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![BU of 1ldd by Molmil](/molmil-images/mine/1ldd) | Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex | Descriptor: | Anaphase Promoting Complex | Authors: | Zheng, N, Schulman, B.A, Song, L, Miller, J.J, Jeffrey, P.D, Wang, P, Chu, C, Koepp, D.M, Elledge, S.J, Pagano, M, Conaway, R.C, Conaway, J.W, Harper, J.W, Pavletich, N.P. | Deposit date: | 2002-04-08 | Release date: | 2002-05-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature, 416, 2002
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1LDK
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![BU of 1ldk by Molmil](/molmil-images/mine/1ldk) | Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex | Descriptor: | CULLIN HOMOLOG, CYCLIN A/CDK2-ASSOCIATED PROTEIN P19, SKP2-like protein type gamma, ... | Authors: | Zheng, N, Schulman, B.A, Song, L, Miller, J.J, Jeffrey, P.D, Wang, P, Chu, C, Koepp, D.M, Elledge, S.J, Pagano, M, Conaway, R.C, Conaway, J.W, Harper, J.W, Pavletich, N.P. | Deposit date: | 2002-04-08 | Release date: | 2002-05-08 | Last modified: | 2019-11-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature, 416, 2002
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1FS2
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![BU of 1fs2 by Molmil](/molmil-images/mine/1fs2) | INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX | Descriptor: | SKP1, SKP2 | Authors: | Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P. | Deposit date: | 2000-09-08 | Release date: | 2000-11-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. Nature, 408, 2000
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1FS1
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![BU of 1fs1 by Molmil](/molmil-images/mine/1fs1) | INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX | Descriptor: | CYCLIN A/CDK2-ASSOCIATED P19, CYCLIN A/CDK2-ASSOCIATED P45 | Authors: | Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P. | Deposit date: | 2000-09-08 | Release date: | 2000-11-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. Nature, 408, 2000
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1FQV
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![BU of 1fqv by Molmil](/molmil-images/mine/1fqv) | Insights into scf ubiquitin ligases from the structure of the skp1-skp2 complex | Descriptor: | SKP1, SKP2 | Authors: | Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P. | Deposit date: | 2000-09-06 | Release date: | 2000-11-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. Nature, 408, 2000
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7K93
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![BU of 7k93 by Molmil](/molmil-images/mine/7k93) | |
6WER
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![BU of 6wer by Molmil](/molmil-images/mine/6wer) | DENV2 NS1 in complex with neutralizing 2B7 Fab fragment | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B7 Fab heavy chain, 2B7 Fab light chain, ... | Authors: | Akey, D.L, Smith, J.L. | Deposit date: | 2020-04-02 | Release date: | 2020-12-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.96 Å) | Cite: | Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction. Science, 371, 2021
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6WEQ
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![BU of 6weq by Molmil](/molmil-images/mine/6weq) | DENV1 NS1 in complex with neutralizing 2B7 Fab fragment | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B7 Fab fragment heavy chain, 2B7 Fab fragment light chain, ... | Authors: | Akey, D.L, Smith, J.L. | Deposit date: | 2020-04-02 | Release date: | 2020-12-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction. Science, 371, 2021
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4RIA
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![BU of 4ria by Molmil](/molmil-images/mine/4ria) | FAN1 Nuclease bound to 5' phosphorylated nicked DNA | Descriptor: | BARIUM ION, DNA (5'-D(*TP*TP*TP*TP*TP*TP*G*AP*GP*GP*CP*GP*TP*G)-3'), DNA (5'-D(P*AP*GP*AP*CP*TP*CP*CP*TP*C)-3'), ... | Authors: | Pavletich, N.P, Wang, R. | Deposit date: | 2014-10-05 | Release date: | 2014-12-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1. Science, 346, 2014
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4RID
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![BU of 4rid by Molmil](/molmil-images/mine/4rid) | Human FAN1 nuclease | Descriptor: | Fanconi-associated nuclease 1 | Authors: | Pavletich, N.P, Wang, R. | Deposit date: | 2014-10-05 | Release date: | 2014-12-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1. Science, 346, 2014
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4RIC
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![BU of 4ric by Molmil](/molmil-images/mine/4ric) | FAN1 Nuclease bound to 5' hydroxyl (dT-dT) single flap DNA | Descriptor: | CALCIUM ION, DNA (5'-D(*GP*CP*TP*GP*AP*GP*GP*AP*GP*TP*CP*T)-3'), DNA (5'-D(*TP*TP*AP*GP*CP*CP*AP*CP*GP*CP*CP*TP*AP*GP*AP*CP*TP*CP*CP*TP*C)-3'), ... | Authors: | Pavletich, N.P, Wang, R. | Deposit date: | 2014-10-05 | Release date: | 2014-12-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1. Science, 346, 2014
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4RI9
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![BU of 4ri9 by Molmil](/molmil-images/mine/4ri9) | |
4RIB
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![BU of 4rib by Molmil](/molmil-images/mine/4rib) | FAN1 Nuclease bound to 5' phosphorylated p(dT) single flap DNA | Descriptor: | CALCIUM ION, DNA (5'-D(*GP*CP*TP*GP*AP*GP*GP*AP*GP*TP*CP*T)-3'), DNA (5'-D(*TP*TP*TP*TP*TP*TP*GP*AP*GP*GP*CP*GP*TP*G)-3'), ... | Authors: | Pavletich, N.P, Wang, R. | Deposit date: | 2014-10-05 | Release date: | 2014-12-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1. Science, 346, 2014
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4RI8
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![BU of 4ri8 by Molmil](/molmil-images/mine/4ri8) | |
8WQD
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![BU of 8wqd by Molmil](/molmil-images/mine/8wqd) | |
8WQC
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![BU of 8wqc by Molmil](/molmil-images/mine/8wqc) | cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CDK5R1 | Descriptor: | Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ... | Authors: | Chen, X, Zhang, K, Xu, C. | Deposit date: | 2023-10-11 | Release date: | 2024-04-03 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase. Nat Commun, 15, 2024
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8WQG
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![BU of 8wqg by Molmil](/molmil-images/mine/8wqg) | cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1) | Descriptor: | Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ... | Authors: | Chen, X, Zhang, K, Xu, C. | Deposit date: | 2023-10-11 | Release date: | 2024-04-03 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.09 Å) | Cite: | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase. Nat Commun, 15, 2024
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8WQI
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![BU of 8wqi by Molmil](/molmil-images/mine/8wqi) | |
8WQA
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![BU of 8wqa by Molmil](/molmil-images/mine/8wqa) | Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1) | Descriptor: | Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | Authors: | Chen, X, Zhang, K, Xu, C. | Deposit date: | 2023-10-11 | Release date: | 2024-04-03 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase. Nat Commun, 15, 2024
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8WQH
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![BU of 8wqh by Molmil](/molmil-images/mine/8wqh) | cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2) | Descriptor: | Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | Authors: | Chen, X, Zhang, K, Xu, C. | Deposit date: | 2023-10-11 | Release date: | 2024-04-03 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase. Nat Commun, 15, 2024
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8WQB
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![BU of 8wqb by Molmil](/molmil-images/mine/8wqb) | Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2) | Descriptor: | Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | Authors: | Chen, X, Zhang, K, Xu, C. | Deposit date: | 2023-10-11 | Release date: | 2024-04-03 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase. Nat Commun, 15, 2024
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8WQE
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![BU of 8wqe by Molmil](/molmil-images/mine/8wqe) | Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CUX1 (conformation 1) | Descriptor: | Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ... | Authors: | Chen, X, Zhang, K, Xu, C. | Deposit date: | 2023-10-11 | Release date: | 2024-04-03 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase. Nat Commun, 15, 2024
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8WQF
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![BU of 8wqf by Molmil](/molmil-images/mine/8wqf) | cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CUX1 (conformation 2) | Descriptor: | Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ... | Authors: | Chen, X, Zhang, K, Xu, C. | Deposit date: | 2023-10-11 | Release date: | 2024-04-03 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase. Nat Commun, 15, 2024
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3S51
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![BU of 3s51 by Molmil](/molmil-images/mine/3s51) | Structure of FANCI | Descriptor: | Fanconi anemia group I protein homolog | Authors: | Pavletich, N.P. | Deposit date: | 2011-05-20 | Release date: | 2011-07-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of the FANCI-FANCD2 complex: insights into the Fanconi anemia DNA repair pathway. Science, 333, 2011
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