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4RI9

FAN1 Nuclease bound to 5' phosphorylated p(dT)/3'(dT-dT-dT-dT-dT-dT-dT-dT) double flap DNA

Summary for 4RI9
Entry DOI10.2210/pdb4ri9/pdb
Related4RI8 4RIA 4RIB 4RIC 4RID
DescriptorFanconi-associated nuclease 1, DNA (5'-D(P*TP*AP*GP*CP*CP*AP*CP*GP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*AP*CP*TP*CP*CP*TP*CP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ... (6 entities in total)
Functional Keywordsnuclease, hydrolase-dna complex, hydrolase/dna
Biological sourceHomo sapiens (human)
More
Cellular locationNucleus : Q9Y2M0
Total number of polymer chains10
Total formula weight181210.29
Authors
Pavletich, N.P.,Wang, R. (deposition date: 2014-10-05, release date: 2014-12-10, Last modification date: 2024-02-28)
Primary citationWang, R.,Persky, N.S.,Yoo, B.,Ouerfelli, O.,Smogorzewska, A.,Elledge, S.J.,Pavletich, N.P.
DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1.
Science, 346:1127-1130, 2014
Cited by
PubMed: 25430771
DOI: 10.1126/science.1258973
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.9 Å)
Structure validation

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