Human FAN1 nuclease

Summary for 4RID

Related4RI8 4RI9 4RIA 4RIB 4RIC
DescriptorFanconi-associated nuclease 1 (1 entity in total)
Functional Keywordsnuclease, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationNucleus  Q9Y2M0
Total number of polymer chains2
Total molecular weight145916.12
Pavletich, N.P.,Wang, R. (deposition date: 2014-10-05, release date: 2014-12-03, Last modification date: 2014-12-10)
Primary citation
Wang, R.,Persky, N.S.,Yoo, B.,Ouerfelli, O.,Smogorzewska, A.,Elledge, S.J.,Pavletich, N.P.
DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1.
Science, 346:1127-1130, 2014
PubMed: 25430771 (PDB entries with the same primary citation)
DOI: 10.1126/science.1258973
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.285183.1%9.1%11.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload