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6WPS
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BU of 6wps by Molmil
Structure of the SARS-CoV-2 spike glycoprotein in complex with the S309 neutralizing antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 neutralizing antibody heavy chain, ...
Authors:Pinto, D, Park, Y.J, Beltramello, M, Walls, A.C, Tortorici, M.A, Bianchi, S, Jaconi, S, Culap, K, Zatta, F, De Marco, A, Peter, A, Guarino, B, Spreafico, R, Cameroni, E, Case, J.B, Chen, R.E, Havenar-Daughton, C, Snell, G, Virgin, H.W, Lanzavecchia, A, Diamond, M.S, Fink, K, Veesler, D, Corti, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-04-27
Release date:2020-05-27
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.
Nature, 583, 2020
6WS6
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BU of 6ws6 by Molmil
Structural and functional analysis of a potent sarbecovirus neutralizing antibody
Descriptor: O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500), S309 antigen-binding (Fab) fragment, heavy chain, ...
Authors:Pinto, D, Park, Y.J, Beltramello, M, Walls, A.C, Tortorici, M.A, Bianchi, S, Jaconi, S, Culap, K, Zatta, F, Marco, A.D, Peter, A, Guarino, B, Spreafico, R, Cameroni, E, Case, J.B, Chen, R.E, Havenar-Daughton, C, Snell, G, Telenti, A, Virgin, H.W, Lanzavecchia, A, Diamond, M.S, Fink, K, Veesler, D, Corti, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-04-30
Release date:2020-05-27
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.
Nature, 583, 2020
6WPT
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BU of 6wpt by Molmil
Structure of the SARS-CoV-2 spike glycoprotein in complex with the S309 neutralizing antibody Fab fragment (open state)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 neutralizing antibody heavy chain, ...
Authors:Pinto, D, Park, Y.J, Beltramello, M, Walls, A.C, Tortorici, M.A, Bianchi, S, Jaconi, S, Culap, K, Zatta, F, De Marco, A, Peter, A, Guarino, B, Spreafico, R, Cameroni, E, Case, J.B, Chen, R.E, Havenar-Daughton, C, Snell, G, Virgin, H.W, Lanzavecchia, A, Diamond, M.S, Fink, K, Veesler, D, Corti, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-04-27
Release date:2020-05-27
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.
Nature, 583, 2020
5UHY
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BU of 5uhy by Molmil
A Human Antibody Against Zika Virus Crosslinks the E Protein to Prevent Infection
Descriptor: ZV67 Fab chain 1, ZV67 Fab chain 2, envelope protein
Authors:Hasan, S.S, Miller, A, Sapparapu, G, Fernandez, E, Klose, T, Long, F, Fokine, A, Porta, J.C, Jiang, W, Diamond, M.S, Crowe Jr, J.E, Kuhn, R.J, Rossmann, M.G.
Deposit date:2017-01-12
Release date:2017-03-29
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:A human antibody against Zika virus crosslinks the E protein to prevent infection.
Nat Commun, 8, 2017
1ZTX
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BU of 1ztx by Molmil
West Nile Virus Envelope Protein DIII in complex with neutralizing E16 antibody Fab
Descriptor: Envelope protein, Heavy Chain of E16 Antibody, Light Chain of E16 Antibody
Authors:Nybakken, G.E, Oliphant, T, Diamond, M.S, Fremont, D.H.
Deposit date:2005-05-27
Release date:2005-10-04
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of West Nile virus neutralization by a therapeutic antibody.
Nature, 437, 2005
2HG0
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BU of 2hg0 by Molmil
Structure of the West Nile Virus envelope glycoprotein
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein
Authors:Nybakken, G.E, Nelson, C.A, Chen, B.R, Diamond, M.S, Fremont, D.H.
Deposit date:2006-06-26
Release date:2006-11-07
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the West Nile virus envelope glycoprotein.
J.Virol., 80, 2006
8FE3
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BU of 8fe3 by Molmil
Structure of dengue virus (DENV2) in complex with prM12, an anti-PrM monoclonal antibody
Descriptor: Envelope protein E, prM protein, prM12 Fab Heavy Chain, ...
Authors:Dowd, A.D, Sirohi, D, Speer, S, Mukherjee, S, Govero, J, Aleshnick, M, Larman, B, Sukupolvi-Petty, S, Sevvana, M, Miller, A.S, Klose, T, Zheng, A, Kielian, M, Kuhn, R.J, Diamond, M.S, Pierson, T.C.
Deposit date:2022-12-05
Release date:2023-02-01
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (10.2 Å)
Cite:prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FE4
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BU of 8fe4 by Molmil
Structure of dengue virus (DENV2) in complex with prM13, an anti-PrM monoclonal antibody
Descriptor: Envelope protein E, prM protein, prM13 Fab Heavy Chain, ...
Authors:Dowd, A.D, Sirohi, D, Speer, S, Mukherjee, S, Govero, J, Aleshnick, M, Larman, B, Sukupolvi-Petty, S, Sevvana, M, Miller, A.S, Klose, T, Zheng, A, Kielian, M, Kuhn, R.J, Diamond, M.S, Pierson, T.C.
Deposit date:2022-12-05
Release date:2023-02-01
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis.
Proc.Natl.Acad.Sci.USA, 120, 2023
6MW9
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BU of 6mw9 by Molmil
CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-3 antibody
Descriptor: E1, E2, EEEV-3 antibody heavy chain, ...
Authors:Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
Deposit date:2018-10-29
Release date:2018-12-19
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
6MWX
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BU of 6mwx by Molmil
CryoEM structure of Chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-69 Antibody
Descriptor: E1, E2, EEEV-69 antibody heavy chain, ...
Authors:Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
Deposit date:2018-10-30
Release date:2018-12-19
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (8.2 Å)
Cite:Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
6MX7
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BU of 6mx7 by Molmil
CryoEM structure of chimeric Eastern Equine Encephalitis Virus: Genome-Binding Capsid N-terminal Domain
Descriptor: Capsid
Authors:Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
Deposit date:2018-10-30
Release date:2018-12-19
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
6MUI
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BU of 6mui by Molmil
CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-42 antibody
Descriptor: E1, E2, EEEV-42 antibody heavy chain, ...
Authors:Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
Deposit date:2018-10-23
Release date:2018-12-19
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
6MWV
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BU of 6mwv by Molmil
CryoEM structure of Chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-58 Antibody
Descriptor: E1, E2, EEEV-58 antibody heavy chain, ...
Authors:Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
Deposit date:2018-10-30
Release date:2018-12-19
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
6MWC
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BU of 6mwc by Molmil
CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-5 antibody
Descriptor: E1, E2, EEEV-5 antibody heavy chain, ...
Authors:Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
Deposit date:2018-10-29
Release date:2018-12-19
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
6MX4
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BU of 6mx4 by Molmil
CryoEM structure of chimeric Eastern Equine Encephalitis Virus
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid, ...
Authors:Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
Deposit date:2018-10-30
Release date:2018-12-19
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
5ANY
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BU of 5any by Molmil
Electron cryo-microscopy of chikungunya virus in complex with neutralizing antibody Fab CHK265
Descriptor: E1, E2, FAB, ...
Authors:Fox, J.M, Long, F, Edeling, M.A, Lin, H, Duijl-Richter, M, Fong, R.H, Kahle, K.M, Smit, J.M, Jin, J, Simmons, G, Doranz, B.J, Crowe, J.E, Fremont, D.H, Rossmann, M.G, Diamond, M.S.
Deposit date:2015-09-08
Release date:2015-11-25
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (16.9 Å)
Cite:Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.
Cell(Cambridge,Mass.), 163, 2015
3IXY
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BU of 3ixy by Molmil
The pseudo-atomic structure of dengue immature virus in complex with Fab fragments of the anti-fusion loop antibody E53
Descriptor: E53 Fab Fragment (chain H), E53 Fab Fragment (chain L), Envelope protein E, ...
Authors:Cherrier, M.V, Kaufmann, B, Nybakken, G.E, Lok, S.M, Warren, J.T, Nelson, C.A, Kostyuchenko, V.A, Holdaway, H.A, Chipman, P.R, Kuhn, R.J, Diamond, M.S, Rossmann, M.G, Fremont, D.H.
Deposit date:2009-02-26
Release date:2009-10-27
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (23 Å)
Cite:Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody
Embo J., 28, 2009
3IXX
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BU of 3ixx by Molmil
The pseudo-atomic structure of West Nile immature virus in complex with Fab fragments of the anti-fusion loop antibody E53
Descriptor: E53 Fab Fragment (chain H), E53 Fab Fragment (chain L), Envelope protein E, ...
Authors:Cherrier, M.V, Kaufmann, B, Nybakken, G.E, Lok, S.M, Warren, J.T, Nelson, C.A, Kostyuchenko, V.A, Holdaway, H.A, Chipman, P.R, Kuhn, R.J, Diamond, M.S, Rossmann, M.G, Fremont, D.H.
Deposit date:2009-02-26
Release date:2009-10-27
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody
Embo J., 28, 2009
3J8D
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BU of 3j8d by Molmil
Cryoelectron microscopy of dengue-Fab E104 complex at pH 5.5
Descriptor: Envelope protein E, antibody E111 Fab fragment, glycoprotein DIII
Authors:Zhang, X.Z, Sheng, J, Austin, S.K, Hoornweg, T, Smit, J.M, Kuhn, R.J, Diamond, M.S, Rossmann, M.G.
Deposit date:2014-10-13
Release date:2014-11-12
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (26 Å)
Cite:Structure of Acidic pH Dengue Virus Showing the Fusogenic Glycoprotein Trimers.
J.Virol., 89, 2015
3J35
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BU of 3j35 by Molmil
Cryo-EM reconstruction of Dengue virus at 37 C
Descriptor: envelope protein
Authors:Zhang, X.Z, Sheng, J, Plevka, P, Kuhn, R.J, Diamond, M.S, Rossmann, M.G.
Deposit date:2013-02-24
Release date:2013-04-10
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Dengue structure differs at the temperatures of its human and mosquito hosts.
Proc.Natl.Acad.Sci.USA, 110, 2013
2R29
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BU of 2r29 by Molmil
Neutralization of dengue virus by a serotype cross-reactive antibody elucidated by cryoelectron microscopy and x-ray crystallography
Descriptor: Envelope protein E, Heavy chain of Fab 1A1D-2, Light chain of Fab 1A1D-2
Authors:Lok, S.M, Kostyuchenko, V.K, Nybakken, G.E, Holdaway, H.A, Battisti, A.J, Sukupolvi-petty, S, Sedlak, D, Fremont, D.H, Chipman, P.R, Roehrig, J.T, Diamond, M.S, Kuhn, R.J, Rossmann, M.G.
Deposit date:2007-08-24
Release date:2007-12-25
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins.
Nat.Struct.Mol.Biol., 15, 2008
2R69
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BU of 2r69 by Molmil
Crystal structure of Fab 1A1D-2 complexed with E-DIII of Dengue virus at 3.8 angstrom resolution
Descriptor: Heavy chain of 1A1D-2, Light chain of 1A1D-2, Major envelope protein E
Authors:Lok, S.M, Kostyuchenko, V.K, Nybakken, G.E, Holdaway, H.A, Battisti, A.J, Sukupolvi-petty, S, Sedlak, D, Fremont, D.H, Chipman, P.R, Roehrig, J.T, Diamond, M.S, Kuhn, R.J, Rossmann, M.G.
Deposit date:2007-09-05
Release date:2007-12-25
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins.
Nat.Struct.Mol.Biol., 15, 2008
7CW3
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BU of 7cw3 by Molmil
Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG (subregion around icosahedral 2-fold vertex)
Descriptor: Capsid protein, E1 glycoprotein, E2 glycoprotein, ...
Authors:Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M.
Deposit date:2020-08-27
Release date:2020-11-04
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
7CW0
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BU of 7cw0 by Molmil
Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG
Descriptor: Capsid protein, E1 glycoprotein, E2 glycoprotein, ...
Authors:Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M.
Deposit date:2020-08-27
Release date:2020-11-04
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
7CW2
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BU of 7cw2 by Molmil
Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-263 (subregion around icosahedral 5-fold vertex)
Descriptor: Capsid protein, E1 glycoprotein, E2 glycoprotein, ...
Authors:Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M.
Deposit date:2020-08-27
Release date:2020-11-04
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020

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