6W3G
 
 | | Rd1NTF2_04 with long sheet | | Descriptor: | Rd1NTF2_04 | | Authors: | Bick, M.J, Basanta, B, Sankaran, B, Baker, D. | | Deposit date: | 2020-03-09 | | Release date: | 2020-04-15 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | An enumerative algorithm for de novo design of proteins with diverse pocket structures.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6W3F
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6W40
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6NAV
 | | Cryo-EM reconstruction of Sulfolobus islandicus LAL14/1 Pilus | | Descriptor: | M9UD72 | | Authors: | Wang, F, Cvirkaite-Krupovic, V, Prangishvili, D, Krupovic, M, Egelman, E.H. | | Deposit date: | 2018-12-06 | | Release date: | 2019-05-08 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | An extensively glycosylated archaeal pilus survives extreme conditions.
Nat Microbiol, 4, 2019
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3T58
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3T59
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8UXS
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4G08
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4G2S
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8VC8
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4G1I
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6MFT
 | | Crystal structure of glycosylated 426c HIV-1 gp120 core G459C in complex with glVRC01 A60C heavy chain | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Weidle, C, Pancera, M, Stamatatos, L, Gray, M. | | Deposit date: | 2018-09-12 | | Release date: | 2018-11-14 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.315 Å) | | Cite: | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018
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6MLU
 | | Cryo-EM structure of lipid droplet formation protein Seipin/BSCL2 | | Descriptor: | Seipin | | Authors: | Sui, X, Arlt, H, Liao, M, Walther, C.T, Farese, V.R. | | Deposit date: | 2018-09-28 | | Release date: | 2018-10-17 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Cryo-electron microscopy structure of the lipid droplet-formation protein seipin.
J. Cell Biol., 217, 2018
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6DLM
 | | DHD127 | | Descriptor: | DHD127_A, DHD127_B | | Authors: | Bick, M.J, Chen, Z, Baker, D. | | Deposit date: | 2018-06-01 | | Release date: | 2018-12-19 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.753 Å) | | Cite: | Programmable design of orthogonal protein heterodimers.
Nature, 565, 2019
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6DMA
 | | DHD15_closed | | Descriptor: | DHD15_closed_A, DHD15_closed_B | | Authors: | Bick, M.J, Chen, Z, Baker, D. | | Deposit date: | 2018-06-04 | | Release date: | 2018-12-19 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.363 Å) | | Cite: | Programmable design of orthogonal protein heterodimers.
Nature, 565, 2019
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6DKM
 | | DHD131 | | Descriptor: | DHD131_A, DHD131_B | | Authors: | Bick, M.J, Chen, Z, Baker, D. | | Deposit date: | 2018-05-29 | | Release date: | 2018-12-19 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Programmable design of orthogonal protein heterodimers.
Nature, 565, 2019
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6DM9
 | | DHD15_extended | | Descriptor: | DHD15_extended_A, DHD15_extended_B, SULFATE ION | | Authors: | Bick, M.J, Chen, Z, Baker, D. | | Deposit date: | 2018-06-04 | | Release date: | 2018-12-19 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Programmable design of orthogonal protein heterodimers.
Nature, 565, 2019
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6DMP
 | | De Novo Design of a Protein Heterodimer with Specificity Mediated by Hydrogen Bond Networks | | Descriptor: | Designed orthogonal protein DHD13_XAAA_A, Designed orthogonal protein DHD13_XAAA_B | | Authors: | Chen, Z, Flores-Solis, D, Sgourakis, N.G, Baker, D. | | Deposit date: | 2018-06-05 | | Release date: | 2018-12-19 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Programmable design of orthogonal protein heterodimers.
Nature, 565, 2019
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6DLC
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8SK7
 | | Cryo-EM structure of designed Influenza HA binder, HA_20, bound to Influenza HA (Strain: Iowa43) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HA_20 minibinder (RFdiffusion-designed), ... | | Authors: | Borst, A.J, Bennett, N.R. | | Deposit date: | 2023-04-18 | | Release date: | 2023-06-14 | | Last modified: | 2023-09-13 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | De novo design of protein structure and function with RFdiffusion.
Nature, 620, 2023
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8TCF
 | | Integrin alpha-v beta-8 in complex with minibinder B8_BP_dsulf | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Campbell, M.G, Fernandez, A, Roy, A, Kraft, J, Baker, D. | | Deposit date: | 2023-06-30 | | Release date: | 2023-09-27 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8.
Nat Commun, 14, 2023
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8TCG
 | | Integrin alpha-v beta-6 in complex with minibinder B6_BP_dslf | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-V heavy chain, ... | | Authors: | Campbell, M.G, Fernandez, A, Roy, A, Kraft, J, Baker, D. | | Deposit date: | 2023-06-30 | | Release date: | 2023-09-27 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8.
Nat Commun, 14, 2023
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8UBG
 | | DpHF19 filament | | Descriptor: | DpHF19,Green fluorescent protein (Fragment) | | Authors: | Lynch, E.M, Shen, H, Kollman, J.M, Baker, D. | | Deposit date: | 2023-09-22 | | Release date: | 2024-04-10 | | Last modified: | 2024-08-07 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | De novo design of pH-responsive self-assembling helical protein filaments.
Nat Nanotechnol, 19, 2024
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8UAO
 | | DpHF18 filament | | Descriptor: | DpHF18 | | Authors: | Lynch, E.M, Shen, H, Kollman, J.M, Baker, D. | | Deposit date: | 2023-09-21 | | Release date: | 2024-04-10 | | Last modified: | 2024-08-07 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | De novo design of pH-responsive self-assembling helical protein filaments.
Nat Nanotechnol, 19, 2024
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6BAA
 | | Cryo-EM structure of the pancreatic beta-cell KATP channel bound to ATP and glibenclamide | | Descriptor: | 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | | Authors: | Martin, G.M, Yoshioka, C, Shyng, S.L. | | Deposit date: | 2017-10-12 | | Release date: | 2017-11-01 | | Last modified: | 2019-12-25 | | Method: | ELECTRON MICROSCOPY (3.63 Å) | | Cite: | Anti-diabetic drug binding site in a mammalian KATPchannel revealed by Cryo-EM.
Elife, 6, 2017
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