Crystal structure of glycosylated 426c HIV-1 gp120 core G459C in complex with glVRC01 A60C heavy chain

Summary for 6MFT

DescriptorHeavy Chain glVRC01, Light chain glVRC01, Gp120, ... (11 entities in total)
Functional Keywordsglycans, germline, immune system-viral protein complex, immune system/viral protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains6
Total molecular weight180022.22
Weidle, C.,Pancera, M.,Stamatatos, L.,Gray, M. (deposition date: 2018-09-12, release date: 2018-11-14, Last modification date: 2020-07-29)
Primary citation
Borst, A.J.,Weidle, C.E.,Gray, M.D.,Frenz, B.,Snijder, J.,Joyce, M.G.,Georgiev, I.S.,Stewart-Jones, G.B.,Kwong, P.D.,McGuire, A.T.,DiMaio, F.,Stamatatos, L.,Pancera, M.,Veesler, D.
Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7:-, 2018
PubMed: 30403372 (PDB entries with the same primary citation)
DOI: 10.7554/eLife.37688
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2934 0.1% 1.6% 12.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-16