6MFT

Crystal structure of glycosylated 426c HIV-1 gp120 core G459C in complex with glVRC01 A60C heavy chain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (H, A)	Heavy Chain glVRC01	polymer	233	25334.3	2		Homo sapiens (Human)
2	B, D (L, B)	Light chain glVRC01	polymer	210	23019.5	2		Homo sapiens (Human)
3	E, F (G, C)	Gp120	polymer	347	38592.0	2	Pfam (PF00516) UniProt (by SIFTS) (M4Q8P8)	Homo sapiens (Human)
4	G, H (D, E)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
5	I (F)	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1073.0	1	In PDB GlyTouCan (G56014GC)
6	J (I)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G22768VO)
7	K, L, M, N, O... (G, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	13	Chemie (NAG)
8	R (G)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
9	Y (C)	CITRIC ACID	non-polymer		192.1	1	Chemie (CIT)
10	AA, Z (C)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
11	BA, CA, DA, EA, FA... (H, L, A, B, G...)	water	water		18.0	325	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	173891.5
Branched	Number of molecules	4
	Total formula weight	2832.6
Non-Polymers*	Number of molecules	17
	Total formula weight	3298.1
All*	Total formula weight	180022.2

*Water molecules are not included.