6BAA

Cryo-EM structure of the pancreatic beta-cell KATP channel bound to ATP and glibenclamide

Summary for 6BAA

• Entry DOI: 10.2210/pdb6baa/pdb
• EMDB information: 7073
• Descriptor: ATP-sensitive inward rectifier potassium channel 11, ATP-binding cassette sub-family C member 8, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: katp, sur1, kir6.2, sulfonylurea receptor, metal transport
• Biological source: Rattus norvegicus (Rat); More
• Total number of polymer chains: 8
• Total formula weight: 887921.93

Authors

Martin, G.M.,Yoshioka, C.,Shyng, S.L. (deposition date: 2017-10-12, release date: 2017-11-01, Last modification date: 2019-12-25)

• Primary citation: Martin, G.M.,Kandasamy, B.,DiMaio, F.,Yoshioka, C.,Shyng, S.L.; Anti-diabetic drug binding site in a mammalian KATPchannel revealed by Cryo-EM.; Elife, 6:-, 2017; PubMed: 29035201; DOI: 10.7554/eLife.31054

Experimental method

ELECTRON MICROSCOPY (3.63 Å)